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Angel of Despair
Angel of Despair 3WhiteWhiteBlackBlack (7)
Creature — Angel (5/5)

Flying

When Angel of Despair enters the battlefield, destroy target permanent.

Magic: The Gathering-Commander (Rare)
Other Versions
Guildpact (Rare)
Argentum Armor
Argentum Armor 6 (6)
Artifact — Equipment

Equipped creature gets +6/+6.

Whenever equipped creature attacks, destroy target permanent.

Equip 6

Scars of Mirrodin (Rare)
Beast Within
Beast Within 2Green (3)
Instant

Destroy target permanent. Its controller puts a 3/3 green Beast creature token onto the battlefield.

Duel Decks: Heroes vs. Monsters (Uncommon)
Other Versions
Planechase 2012 Edition (Uncommon)New Phyrexia (Uncommon)
Desert Twister
Desert Twister 4GreenGreen (6)
Sorcery

Destroy target permanent.

Masters Edition III (Uncommon)
Other Versions
Mercadian Masques (Uncommon)Fifth Edition (Uncommon)Fourth Edition (Uncommon)Revised Edition (Uncommon)Arabian Nights (Uncommon)
Despotic Scepter
Despotic Scepter 1 (1)
Artifact

Tap: Destroy target permanent you own. It can't be regenerated.

Masters Edition II (Rare)
Other Versions
Ice Age (Rare)
Hydroblast
Hydroblast Blue (1)
Instant

Choose one — Counter target spell if it's red; or destroy target permanent if it's red.

Masters Edition (Common)
Other Versions
Fifth Edition (Uncommon)Ice Age (Common)
Karmic Justice
Karmic Justice 2White (3)
Enchantment

Whenever a spell or ability an opponent controls destroys a noncreature permanent you control, you may destroy target permanent that opponent controls.

Odyssey (Rare)
Lux Cannon
Lux Cannon 4 (4)
Artifact

Tap: Put a charge counter on Lux Cannon.

Tap, Remove three charge counters from Lux Cannon: Destroy target permanent.

Scars of Mirrodin (Mythic Rare)
Necrotic Sliver
Necrotic Sliver 1WhiteBlack (3)
Creature — Sliver (2/2)

All Slivers have "3, Sacrifice this permanent: Destroy target permanent."

Premium Deck Series: Slivers (Uncommon)
Other Versions
Planar Chaos (Uncommon)
Pentarch Paladin
Pentarch Paladin 2WhiteWhiteWhite (5)
Creature — Human Knight (3/3)

Flanking (Whenever a creature without flanking blocks this creature, the blocking creature gets -1/-1 until end of turn.)

As Pentarch Paladin enters the battlefield, choose a color.

WhiteWhite, Tap: Destroy target permanent of the chosen color.

Time Spiral (Rare)
Pyroblast
Pyroblast Red (1)
Instant

Choose one — Counter target spell if it's blue; or destroy target permanent if it's blue.

Masters Edition (Common)
Other Versions
Fifth Edition (Uncommon)Ice Age (Common)
Reaper King
Reaper King Two or WhiteTwo or BlueTwo or BlackTwo or RedTwo or Green (10)
Legendary Artifact Creature — Scarecrow (6/6)

(Two or White can be paid with any two mana or with White. This card's converted mana cost is 10.)

Other Scarecrow creatures you control get +1/+1.

Whenever another Scarecrow enters the battlefield under your control, destroy target permanent.

Shadowmoor (Rare)
Spine of Ish Sah
Spine of Ish Sah 7 (7)
Artifact

When Spine of Ish Sah enters the battlefield, destroy target permanent.

When Spine of Ish Sah is put into a graveyard from the battlefield, return Spine of Ish Sah to its owner's hand.

Commander 2013 Edition (Rare)
Other Versions
Mirrodin Besieged (Rare)
Tornado
Tornado 4Green (5)
Enchantment

Cumulative upkeep Green (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)

2Green, Pay 3 life for each velocity counter on Tornado: Destroy target permanent and put a velocity counter on Tornado. Activate this ability only once each turn.

Masters Edition (Rare)
Other Versions
Alliances (Rare)
Ulamog, the Infinite Gyre
Ulamog, the Infinite Gyre 11 (11)
Legendary Creature — Eldrazi (10/10)

When you cast Ulamog, the Infinite Gyre, destroy target permanent.

Indestructible

Annihilator 4 (Whenever this creature attacks, defending player sacrifices four permanents.)

When Ulamog is put into a graveyard from anywhere, its owner shuffles his or her graveyard into his or her library.

From the Vault: Legends (Mythic Rare)
Other Versions
Rise of the Eldrazi (Mythic Rare)
Vindicate
Vindicate 1WhiteBlack (3)
Sorcery

Destroy target permanent.

Apocalypse (Rare)