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Eternal Isolation
Eternal Isolation 1White (2)
Sorcery

Put target creature with power 4 or greater on the bottom of its owner's library.

Core Set 2020 (Uncommon)
Fear of Isolation
Fear of Isolation 1Blue (2)
Enchantment Creature — Nightmare (2/3)

As an additional cost to cast this spell, return a permanent you control to its owner's hand.

Flying

Duskmourn: House of Horror (Uncommon)
Isolate
Isolate White (1)
Instant

Exile target permanent with mana value 1.

Core Set 2019 (Rare)
Isolated Chapel
Isolated Chapel (0)
Land

Isolated Chapel enters tapped unless you control a Plains or a Swamp.

Tap: Add White or Black.

Outlaws of Thunder Junction Commander (Rare)
Other Versions
Innistrad (Rare)
Modern Event Deck 2014 (Rare)
Dominaria (Rare)
Dominaria Remastered (Rare)
The Lord of the Rings: Tales of Middle Earth Commander (Rare)
The Lost Caverns of Ixalan Commander (Rare)
Magic The Gathering—Fallout (Rare)
Isolated Watchtower
Isolated Watchtower (0)
Land

Tap: Add Colorless.

2, Tap: Scry 1, then you may reveal the top card of your library. If a basic land card is revealed this way, put it onto the battlefield tapped. Activate only if an opponent controls at least two more lands than you.

Commander 2018 (Rare)
Isolation at Orthanc
Isolation at Orthanc 3Blue (4)
Instant

Put target creature into its owner's library second from the top.

The Lord of the Rings: Tales of Middle Earth (Common)
Isolation Cell
Isolation Cell 4 (4)
Artifact

Whenever an opponent casts a creature spell, that player loses 2 life unless they pay 2.

New Phyrexia (Uncommon)
Isolation Zone
Isolation Zone 2WhiteWhite (4)
Enchantment

When Isolation Zone enters, exile target creature or enchantment an opponent controls until Isolation Zone leaves the battlefield. (That permanent returns under its owner's control.)

Oath of the Gatewatch (Common)
Strength of Isolation
Strength of Isolation 1White (2)
Enchantment — Aura

Enchant creature

Enchanted creature gets +1/+2 and has protection from black.

Madness White (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Torment (Uncommon)
Temporal Isolation
Temporal Isolation 1White (2)
Enchantment — Aura

Flash

Enchant creature

Enchanted creature has shadow. (It can block or be blocked by only creatures with shadow.)

Prevent all damage that would be dealt by enchanted creature.

Time Spiral Remastered (Common)
Other Versions
Time Spiral (Common)
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