How about a blue deck with 4 of these and plenty of Thrummingbird, Steady Progress, Fuel for the Cause, and Inexorable Tide, Tezzeret's Gambit, and Viral Drake.

Don't forget Blighted Agent for more infect to go along with all that proliferation, and what are you going to do with your ridiculous supply of colorless mana? How about a Blightsteel Colossus (how fitting that he too has infect)! Game over.

Might be worth it to go blue/black and throw in Grim Affliction, Spread the Sickness, and any number of other infect creatures (there are many in blue and black).