| 92 | Simic Initiate | Dany Orizio | Green | C | Dissension |
| 162 | Simic Initiate | Dany Orizio | Green | C | Modern Masters 2015 Edition |
| 237 | Simic Keyrune | Daniel Ljunggren | | U | Gatecrash |
| 265 | Simic Keyrune | Daniel Ljunggren | | U | Commander 2015 |
| 240 | Simic Locket | Yeong-Hao Han | | C | Ravnica Allegiance |
| 50 | Simic Manipulator | Maciej Kuciara | Blue | R | Gatecrash |
| 93 | Simic Ragworm | Nick Percival | Green | C | Dissension |
| 130 | Simic Signet | Mike Sass | | U | Guild Kit: Simic |
| 166 | Simic Signet | Greg Hildebrandt | | C | Dissension |
| 215 | Simic Signet | Greg Hildebrandt | | C | Commander Anthology 2018 |
| 216 | Simic Signet | Mike Sass | | C | Commander Anthology 2018 |
| 227 | Simic Signet | Mike Sass | | U | Modern Masters 2017 Edition |
| 228 | Simic Signet | Mike Sass | | C | Ravnica Clue Edition |
| 229 | Simic Signet | Mike Sass | | C | Commander Anthology |
| 236 | Simic Signet | Mike Sass | | U | Murders at Karlov Manor Commander |
| 252 | Simic Signet | Mike Sass | | U | Duskmourn: House of Horror Commander |
| 258 | Simic Signet | Mike Sass | | C | Commander 2013 Edition |
| 259 | Simic Signet | Greg Hildebrandt | | C | Magic: The Gathering-Commander |
| 262 | Simic Signet | Mike Sass | | C | Commander 2021 |
| 266 | Simic Signet | Mike Sass | | C | Commander 2015 |
| 269 | Simic Signet | Greg Hildebrandt | | U | Ravnica Remastered |
| 270 | Simic Signet | Mike Sass | | C | Commander 2016 |
| 312 | Simic Signet | Mike Sass | | U | The Lost Caverns of Ixalan Commander |
| 378 | Simic Signet | Mike Sass | | C | March of the Machine Commander |
| 471 | Simic Signet | Mike Sass | | C | Commander Legends |
| 56 | Simic Sky Swallower | rk post | Blue/Green | R | Duel Decks: Elspeth vs. Kiora |
| 124 | Simic Sky Swallower | rk post | Blue/Green | R | Guild Kit: Simic |
| 130 | Simic Sky Swallower | rk post | Blue/Green | R | Dissension |
| 182 | Simic Sky Swallower | rk post | Blue/Green | R | Modern Masters 2017 Edition |
| 208 | Simic Sky Swallower | rk post | Blue/Green | R | Iconic Masters |
| 226 | Simic Sky Swallower | rk post | Blue/Green | R | Magic: The Gathering-Commander |
| 452 | Simic Sky Swallower | rk post | Blue/Green | R | Commander Legends |
| Simoon | Randy Gallegos | Red/Green | U | Visions |
| 272 | Simoon | Tony Szczudlo | Red/Green | U | Invasion |
| 154 | Simple | Parente | White/Green | U | Dissension |
| 269 | Simplify | Greg & Tim Hildebrandt | Green | C | Odyssey |
| Simulacrum | Mark Poole | Black | U | Fourth Edition |
| Simulacrum | Mark Poole | Black | U | Revised Edition |
| Simulacrum | Mark Poole | Black | U | Unlimited Edition |
| Simulacrum | Mark Poole | Black | U | Limited Edition Beta |
| Simulacrum | Mark Poole | Black | U | Limited Edition Alpha |
| 6 | Simulacrum Synthesizer | Anton Solovianchyk | Blue | M | Outlaws of Thunder Junction: The Big Score |
| 36 | Simulacrum Synthesizer | Svetlin Velinov | Blue | M | Outlaws of Thunder Junction: The Big Score |
| 71 | Simulacrum Synthesizer | Anton Solovianchyk | Blue | M | Outlaws of Thunder Junction: The Big Score |
| 45 | Sin Collector | Mike Bierek | White/Black | U | Guild Kit: Orzhov |
| 103 | Sin Collector | Mike Bierek | White/Black | U | Dragon's Maze |
| 183 | Sin Collector | Mike Bierek | White/Black | U | Modern Masters 2017 Edition |
| 177 | Sin Prodder | Jack Wang | Red | R | Shadows Over Innistrad Remastered |
| 181 | Sin Prodder | Jack Wang | Red | R | Shadows over Innistrad |
| 363 | Sin Prodder | Jack Wang | Red | R | Jumpstart |
| Sindbad | Julie Baroh | Blue | U | Fourth Edition |
| Sindbad | Julie Baroh | Blue | U | Arabian Nights |
| 31 | Sindbad | Julie Baroh | Blue | S | Time Spiral "Timeshifted" |
| 32 | Sinew Dancer | Campbell White | White | C | Phyrexia: All Will Be One |
| 286 | Sinew Dancer | Kekai Kotaki | White | C | Phyrexia: All Will Be One |
| 30 | Sinew Sliver | Steven Belledin | White | C | Planar Chaos |
| 44 | Sinew Sliver | Steven Belledin | White | C | Time Spiral Remastered |
| 837 | Sinew Sliver | Steven Belledin | White | C | Commander Masters |
| 71 | Singe | John Avon | Red | C | Planeshift |
| 45 | Singe-Mind Ogre | Daarken | Black/Red | C | Alara Reborn |
| 66 | Singer of Swift Rivers | Gabor Szikszai | Blue/Green | R | The Lost Caverns of Ixalan Commander |
| 98 | Singer of Swift Rivers | Gabor Szikszai | Blue/Green | R | The Lost Caverns of Ixalan Commander |
| 55 | Singing Bell Strike | Chase Stone | Blue | C | Khans of Tarkir |
| Singing Tree | Rob Alexander | Green | R | Arabian Nights |
| 130 | Singing Tree | Rob Alexander | Green | U | Masters Edition |
| 30 | Single Combat | Livia Prima | White | R | War of the Spark |
| 172 | Single Combat | Josh Hass | White | R | Magic The Gathering—Fallout |
| 458 | Single Combat | Josh Hass | White | R | Magic The Gathering—Fallout |
| 30 | Sinister Concierge | Tomas Duchek | Blue | R | Streets of New Capenna Commander |
| 131 | Sinister Concierge | Tomas Duchek | Blue | R | Streets of New Capenna Commander |
| 135 | Sinister Concoction | Zack Stella | Black | U | Shadows over Innistrad |
| 113 | Sinister Monolith | Adam Paquette | Black | U | Bloomburrow |
| 29 | Sinister Possession | Anthony Palumbo | Black | C | Dragon's Maze |
| 22 | Sinister Reflections | John Stanko | Blue | R | Innistrad: Midnight Hunt Alchemy |
| 54 | Sinister Sabotage | Mathias Kollros | Blue | U | Guilds of Ravnica |
| 61 | Sinister Sabotage | Mathias Kollros | Blue | C | Ravnica Remastered |
| 99 | Sinister Starfish | Nils Hamm | Black | C | Modern Horizons 2 |
| 140 | Sinister Starfish | Nils Hamm | Black | C | Murders at Karlov Manor Commander |
| 54 | Sinister Strength | Terese Nielsen | Black | C | Planeshift |
| 30 | Sinister Waltz | Jason Rainville | Black/Red | R | Innistrad: Crimson Vow Commander |
| 68 | Sinister Waltz | Jason Rainville | Black/Red | R | Innistrad: Crimson Vow Commander |
| 241 | Sink into Stupor | Peter Polach | Blue | U | Modern Horizons 3 |
| 89 | Sink into Takenuma | Pat Lee | Black | C | Saviors of Kamigawa |
| Sinkhole | Sandra Everingham | Black | C | Unlimited Edition |
| Sinkhole | Sandra Everingham | Black | C | Limited Edition Beta |
| Sinkhole | Sandra Everingham | Black | C | Limited Edition Alpha |
| 97 | Sinkhole | Sandra Everingham | Black | R | Masters Edition IV |
| 106 | Sinkhole | Jonas De Ro | Black | R | Eternal Masters |
| 51 | Sinking Feeling | Ron Brown | Blue | C | Shadowmoor |
| 12 | Sinner's Judgment | Svetlin Velinov | White | M | Innistrad: Crimson Vow |
| 348 | Sinner's Judgment | Svetlin Velinov | White | M | Innistrad: Crimson Vow |
| 106 | Sins of the Past | Jeremy Jarvis | Black | R | Ravnica: City of Guilds |
| 16 | Sinstriker's Will | Ben Thompson | White | U | Guildpact |
| 76 | Sinuous Benthisaur | John Tedrick | Blue | U | The Lost Caverns of Ixalan |
| 163 | Sinuous Predator | Slawomir Maniak | | U | Eldritch Moon |
| 45 | Sinuous Striker | Svetlin Velinov | Blue | U | Hour of Devastation |
| 46 | Sinuous Vermin | Jason Kang | Black | C | Conspiracy: Take the Crown |
| 466 | Sinuous Vermin | Jason Kang | Black | C | Jumpstart 2022 |
| 144 | Siona, Captain of the Pyleas | Chris Rallis | White/Green | U | Wilds of Eldraine Commander |
| 226 | Siona, Captain of the Pyleas | Chris Rallis | White/Green | U | Theros Beyond Death |
| 106 | Sip of Hemlock | Nils Hamm | Black | C | Theros |
| 54 | Siphon Insight | Michal Ivan | Blue/Black | R | Outlaws of Thunder Junction Breaking News |
| 241 | Siphon Insight | Livia Prima | Blue/Black | R | Innistrad: Midnight Hunt |
| 242 | Siphon Insight | Livia Prima | Blue/Black | R | Outlaws of Thunder Junction Commander |
| 375 | Siphon Insight | Livia Prima | Blue/Black | R | Innistrad: Midnight Hunt |
| Sir Shandlar of Eberyn | Andi Rusu | White/Green | U | Legends |
| 174 | Sir Shandlar of Eberyn | Andi Rusu | White/Green | C | Masters Edition III |
| 104 | Sire of Insanity | Peter Mohrbacher | Black/Red | R | Dragon's Maze |
| 1 | Sire of Seven Deaths | Lius Lasahido | | M | Magic: The Gathering Foundations |
| 292 | Sire of Seven Deaths | Alexander Mokhov | | M | Magic: The Gathering Foundations |
| 362 | Sire of Seven Deaths | Alexander Mokhov | | M | Magic: The Gathering Foundations |
| 206 | Sire of Stagnation | Tyler Jacobson | Blue/Black | M | Battle for Zendikar |
| 272 | Sire of Stagnation | Tyler Jacobson | Blue/Black | M | Modern Horizons 3 Commander |
| 85 | Sire of the Storm | Arnie Swekel | Blue | U | Champions of Kamigawa |
| 113 | Sire of the Storm | Arnie Swekel | Blue | U | Innistrad: Crimson Vow Commander |
| 78 | Siren Lookout | Chris Rallis | Blue | C | Ixalan |
| 50 | Siren of the Fanged Coast | Michael C. Hayes | Blue | U | Born of the Gods |
| 155 | Siren of the Silent Song | Anthony Palumbo | Blue/Black | U | Born of the Gods |
| 54 | Siren Reaver | Tomasz Jedruszek | Blue | U | Rivals of Ixalan |
| 161 | Siren Song Lyre | James Paick | | U | Born of the Gods |
| 79 | Siren Stormtamer | Josu Hernaiz | Blue | U | Ixalan |
| 96 | Siren Stormtamer | Josu Hernaiz | Blue | U | Commander Legends |
| 171 | Siren Stormtamer | Josu Hernaiz | Blue | U | The Lost Caverns of Ixalan Commander |
| Siren's Call | Anson Maddocks | Blue | U | Fourth Edition |
| Siren's Call | Anson Maddocks | Blue | U | Revised Edition |
| Siren's Call | Anson Maddocks | Blue | U | Unlimited Edition |
| Siren's Call | Anson Maddocks | Blue | U | Limited Edition Beta |
| Siren's Call | Anson Maddocks | Blue | U | Limited Edition Alpha |
| 80 | Siren's Ruse | Ben Maier | Blue | C | Ixalan |
| Sirocco | Alan Rabinowitz | Red | U | Mirage |
| 29 | Sisay, Weatherlight Captain | Anna Steinbauer | White | R | Modern Horizons |
| 33 | Sisay's Ingenuity | Paolo Parente | Blue | C | Planeshift |
| Sisay's Ring | Donato Giancola | | C | Visions |
| 315 | Sisay's Ring | David Martin | | U | Seventh Edition |
| 340 | Sisay's Ring | Donato Giancola | | C | Commander Legends |
| 141 | Sister Hospitaller | Games Workshop | White/Black | R | Warhammer 40,000 Commander |
| 26 | Sister of Silence | Games Workshop | Blue | R | Warhammer 40,000 Commander |
| 142 | Sister Repentia | Seseon Yoon | White/Black | R | Warhammer 40,000 Commander |
| 109 | Sisterhood of Karn | Yuliya Litvinova | Green | R | Doctor Who Commander |
| 399 | Sisterhood of Karn | Yuliya Litvinova | Green | R | Doctor Who Commander |
| 71 | Sisters of Stone Death | Donato Giancola | Black/Green | R | Guild Kit: Golgari |
| 231 | Sisters of Stone Death | Donato Giancola | Black/Green | R | Ravnica: City of Guilds |
| Sisters of the Flame | Jesper Myrfors | Red | C | Fourth Edition |
| Sisters of the Flame | Jesper Myrfors | Red | U | The Dark |
| Sivitri Scarzam | NéNé Thomas | Blue/Black | U | Chronicles |
| Sivitri Scarzam | NéNé Thomas | Blue/Black | U | Legends |
| 175 | Sivitri Scarzam | NéNé Thomas | Blue/Black | C | Masters Edition III |
| 43 | Sivitri, Dragon Master | Livia Prima | Blue/Black | M | Dominaria United Commander |
| 148 | Sivriss, Nightmare Speaker | Tuan Duong Chu | Black | U | Commander Legends: Battle for Baldur's Gate |
| 393 | Sivriss, Nightmare Speaker | Justine Jones | Black | U | Commander Legends: Battle for Baldur's Gate |
| 21 | Sivvi's Ruse | Kev Walker | White | U | Nemesis |
| 22 | Sivvi's Valor | Jeff Miracola | White | R | Nemesis |
| 169 | Six | Andrew Mar | Green | R | Modern Horizons 3 |
| 370 | Six | Ivan Shavrin | Green | R | Modern Horizons 3 |
| 430 | Six | Andrew Mar | Green | R | Modern Horizons 3 |
| 484 | Six | Andrew Mar | Green | R | Modern Horizons 3 |
| 92 | Six-Sided Die | Ben Wootten | Black | C | Unfinity |
| 187 | Sixth Sense | Zoltan Boros | Green | U | Amonkhet |
| 220 | Sixth Sense | Zoltan Boros | Green | U | Amonkhet Remastered |
| 56 | Six-y Beast | Anson Maddocks | Red | U | Unsanctioned |
| 89 | Six-y Beast | Anson Maddocks | Red | U | Unhinged |
| 213 | Sizzle | Brian Snoddy | Red | C | Mercadian Masques |
| 224 | Sizzle | Christopher Moeller | Red | C | Eighth Edition |
| 162 | Sizzling Barrage | Johann Bodin | Red | C | Zendikar Rising |
| 123 | Sizzling Soloist | Véronique Meignaud | Red | U | Streets of New Capenna |
| 74 | Skaab Goliath | Volkan Baga | Blue | U | Magic Origins |
| 76 | Skaab Goliath | Volkan Baga | Blue | U | Innistrad |
| 97 | Skaab Goliath | Volkan Baga | Blue | C | Commander Legends |
| 77 | Skaab Ruinator | Chris Rahn | Blue | M | Innistrad |
| 128 | Skaab Ruinator | Chris Rahn | Blue | M | Duskmourn: House of Horror Commander |
| 75 | Skaab Wrangler | Billy Christian | Blue | U | Innistrad: Midnight Hunt |
| 303 | Skalla Wolf | Lius Lasahido | Green | R | Core Set 2019 |
| 255 | Skanos Dragonheart | Daarken | Green | U | Commander Legends: Battle for Baldur's Gate |
| 410 | Skanos Dragonheart | Mark A. Nelson | Green | U | Commander Legends: Battle for Baldur's Gate |
| 133 | Skarrg Goliath | Scott Chou | Green | R | Gatecrash |
| 196 | Skarrg Guildmage | Aleksi Briclot | Red/Green | U | Gatecrash |
| 73 | Skarrg, the Rage Pits | Martina Pilcerova | | U | Duel Decks: Heroes vs. Monsters |
| 127 | Skarrg, the Rage Pits | Martina Pilcerova | | U | Planechase Anthology |
| 127 | Skarrg, the Rage Pits | Martina Pilcerova | | U | Planechase 2012 Edition |
| 163 | Skarrg, the Rage Pits | Martina Pilcerova | | U | Guildpact |
| 57 | Skarrgan Firebird | Kev Walker | Red | U | Archenemy: Nicol Bolas |
| 57 | Skarrgan Firebird | Kev Walker | Red | R | Duel Decks: Heroes vs. Monsters |
| 77 | Skarrgan Firebird | Kev Walker | Red | R | Guildpact |
| 81 | Skarrgan Firebird | Kev Walker | Red | R | Guild Kit: Gruul |
| 123 | Skarrgan Firebird | Kev Walker | Red | U | Modern Masters 2015 Edition |
| 114 | Skarrgan Hellkite | Svetlin Velinov | Red | M | Ravnica Allegiance |
| 50 | Skarrgan Pit-Skulk | Liam Sharp | Green | C | Duel Decks: Mind vs. Might |
| 84 | Skarrgan Pit-Skulk | Liam Sharp | Green | C | Guild Kit: Gruul |
| 96 | Skarrgan Pit-Skulk | Liam Sharp | Green | C | Guildpact |
| 60 | Skarrgan Skybreaker | Dan Scott | Red/Green | U | Duel Decks: Heroes vs. Monsters |
| 130 | Skarrgan Skybreaker | Dan Scott | Red/Green | U | Guildpact |
| 52 | Skatewing Spy | Grzegorz Rutkowski | Blue | U | Ravnica Allegiance |
| 140 | Skeletal Changeling | Alan Pollack | Black | C | Lorwyn |
| Skeletal Crocodile | Mike Dringenberg | Black | C | Portal |
| 116 | Skeletal Grimace | Eric Deschamps | Black | C | Innistrad |
| 88 | Skeletal Kathari | Carl Critchlow | Black | C | Shards of Alara |
| 124 | Skeletal Scrying | Bob Petillo | Black | U | Magic: The Gathering—Conspiracy |
| 125 | Skeletal Scrying | Bob Petillo | Black | U | Commander 2017 |
| 161 | Skeletal Scrying | Bob Petillo | Black | U | Odyssey |
| 162 | Skeletal Scrying | Bob Petillo | Black | U | Commander 2014 |
| Skeletal Snake | John Matson | Black | C | Portal |