| 34 | Scrollshift | Bram Sels | White | C | March of the Machine |
| 53 | Scrounge | Pete Venters | Black | U | Darksteel |
| 23 | Sculpting Steel | Magali Villeneuve | | S | Masterpiece Series: Kaladesh Inventions |
| 50 | Sculpting Steel | Heather Hudson | | R | The Brothers' War Retro Artifacts |
| 113 | Sculpting Steel | Heather Hudson | | R | The Brothers' War Retro Artifacts |
| 238 | Sculpting Steel | Heather Hudson | | R | Mirrodin |
| 247 | Sculpting Steel | Pierre Loyvet | | R | Warhammer 40,000 Commander |
| 261 | Sculpting Steel | Heather Hudson | | R | Commander 2021 |
| 286 | Sculpting Steel | Heather Hudson | | R | Double Masters |
| 302 | Sculpting Steel | Magali Villeneuve | | M | Kaladesh Remastered |
| 342 | Sculpting Steel | Heather Hudson | | R | Tenth Edition |
| 374 | Sculpting Steel | Heather Hudson | | R | March of the Machine Commander |
| 172 | Scurry Oak | Mark Zug | Green | U | Modern Horizons 2 |
| 203 | Scute Swarm | Alex Konstad | Green | R | Zendikar Rising |
| 205 | Scute Swarm | Alex Konstad | Green | R | Outlaws of Thunder Junction Commander |
| 245 | Scute Swarm | Alex Konstad | Green | R | Modern Horizons 3 Commander |
| 308 | Scute Swarm | Roman Kuteynikov | Green | R | Zendikar Rising |
| 310 | Scute Swarm | Alex Konstad | Green | R | Streets of New Capenna Commander |
| 238 | Scuttlemutt | Jeremy Jarvis | | U | Core Set 2020 |
| 263 | Scuttlemutt | Jeremy Jarvis | | C | Shadowmoor |
| 484 | Scuttlemutt | Jeremy Jarvis | | U | Jumpstart |
| 244 | Scuttling Butler | Gaboleps | | U | Streets of New Capenna |
| 42 | Scuttling Sentinel | Betty Jiang | Blue/Green | U | Ravnica Clue Edition |
| 68 | Scuttling Sliver | Mike Bierek | Blue | U | Modern Horizons |
| 165 | Scytheclaw Raptor | John Tedrick | Red | U | The Lost Caverns of Ixalan |
| 323 | Scytheclaw Raptor | Sidharth Chaturvedi | Red | U | The Lost Caverns of Ixalan |
| Sea Drake | Rebecca Guay | Blue | U | Portal Second Age |
| 64 | Sea Drake | Rebecca Guay | Blue | R | Masters Edition II |
| 92 | Sea Drake | Rebecca Guay | Blue | R | Vintage Masters |
| 268 | Sea Drake | Rebecca Guay | Blue | U | Modern Horizons 2 |
| 10 | Sea Gate Oracle | Daniel Ljunggren | Blue | C | Duel Decks: Jace vs. Vraska |
| 38 | Sea Gate Oracle | Daniel Ljunggren | Blue | C | Game Night: Free-For-All |
| 43 | Sea Gate Oracle | Daniel Ljunggren | Blue | C | Kaldheim Commander |
| 48 | Sea Gate Oracle | Daniel Ljunggren | Blue | C | Modern Masters 2017 Edition |
| 85 | Sea Gate Oracle | Daniel Ljunggren | Blue | C | Rise of the Eldrazi |
| 92 | Sea Gate Oracle | Daniel Ljunggren | Blue | C | Commander 2017 |
| 124 | Sea Gate Oracle | Daniel Ljunggren | Blue | C | Commander 2014 |
| 173 | Sea Gate Oracle | Daniel Ljunggren | Blue | C | Jumpstart |
| 95 | Sea Hag | Andrea Piparo | Blue | C | Commander Legends: Battle for Baldur's Gate |
| Sea Troll | Daniel Gelon | Blue | U | Homelands |
| 66 | Sea-Dasher Octopus | Chris Seaman | Blue | R | Ikoria: Lair of Behemoths |
| 78 | Seafloor Stalker | Cristi Balanescu | Blue | C | Zendikar Rising |
| 35 | Seal from Existence | Anato Finnstark | White | U | March of the Machine |
| 53 | Seal of Doom | Ralph Horsley | Black | C | Dissension |
| 70 | Seal of Doom | Christopher Moeller | Black | C | Nemesis |
| 83 | Seal of Doom | Ralph Horsley | Black | U | Modern Masters 2017 Edition |
| 135 | Seal of Doom | Ralph Horsley | Black | C | Commander 2015 |
| 27 | Search for Glory | Kieran Yanner | White | R | Kaldheim |
| 340 | Search for Glory | Kieran Yanner | White | R | Kaldheim |
| 102 | Search for Survivors | Mark Romanoski | Red | R | Prophecy |
| 77 | Search for Tomorrow | Randy Gallegos | Green | C | Planechase |
| 137 | Search for Tomorrow | Greg Staples | Green | C | Dominaria United Commander |
| 161 | Search for Tomorrow | Randy Gallegos | Green | C | Modern Masters |
| 185 | Search for Tomorrow | Randy Gallegos | Green | C | Iconic Masters |
| 216 | Search for Tomorrow | Randy Gallegos | Green | C | Time Spiral |
| 229 | Search for Tomorrow | Greg Staples | Green | C | Time Spiral Remastered |
| 234 | Search for Tomorrow | Eddie Schillo | Green | C | Doctor Who Commander |
| 436 | Search for Tomorrow | Randy Gallegos | Green | C | Commander Legends |
| 834 | Search for Tomorrow | Greg Staples | Green | C | Commander Legends: Battle for Baldur's Gate |
| 258 | Searchlight Companion | Rudy Siswanto | | C | Kamigawa: Neon Dynasty |
| 119 | Searchlight Geist | Steven Belledin | Black | C | Avacyn Restored |
| 163 | Searing Barb | Tiffany Turrill | Red | C | March of the Machine |
| 27 | Searing Meditation | Dave Dorman | White/Red | R | Duel Decks: Ajani vs. Nicol Bolas |
| 226 | Searing Meditation | Dave Dorman | White/Red | R | Ravnica: City of Guilds |
| 165 | Searing Rays | Doug Chaffee | Red | U | Invasion |
| Searing Spear Askari | Richard Kane Ferguson | Red | C | Mirage |
| 311 | Seashell Cameo | Tony Szczudlo | | U | Invasion |
| Seasinger | John Matson | Blue | U | Fifth Edition |
| Seasinger | Amy Weber | Blue | U | Fallen Empires |
| 49 | Seasinger | Amy Weber | Blue | U | Masters Edition |
| 205 | Season of Renewal | Rovina Cai | Green | C | Kamigawa: Neon Dynasty |
| Season of the Witch | Jesper Myrfors | Black | R | The Dark |
| 174 | Seasonal Ritual | Johannes Voss | Green | C | Throne of Eldraine |
| 58 | Seasoned Buttoneer | Tomek Larek | Blue | C | Unfinity |
| 123 | Seasoned Pyromancer | Cynthia Sheppard | Red | M | Double Masters 2022 |
| 145 | Seasoned Pyromancer | Cynthia Sheppard | Red | M | Modern Horizons |
| 363 | Seasoned Pyromancer | Steve Prescott | Red | M | Double Masters 2022 |
| 454 | Seasoned Pyromancer | Cynthia Sheppard | Red | M | Double Masters 2022 |
| Seasoned Tactician | Dan Frazier | White | U | Alliances |
| 63 | Seasoned Weaponsmith (playtest) | Mark L. Gottlieb | Red | C | Mystery Booster |
| 29 | Second Breakfast | Christina Kraus | White | C | The Lord of the Rings: Tales of Middle Earth |
| 480 | Second Breakfast | Christina Kraus | White | C | The Lord of the Rings: Tales of Middle Earth |
| 41 | Second Chance | Mark Tedin | Blue | R | Urza's Legacy |
| 33 | Second Sight | Luca Zontini | Blue | U | Darksteel |
| 20 | Second Sunrise | Greg Staples | White | R | Mirrodin |
| 57 | Second Wind | Matt Stewart | Blue | U | Future Sight |
| 26 | Secret Rendezvous | Manuel Castañón | White | U | Strixhaven: School of Mages |
| 48 | Secrets of the Dead | Eytan Zana | Blue | U | Dark Ascension |
| 95 | Secrets of the Dead | Eytan Zana | Blue | U | Commander 2019 |
| 52 | Secrets of the Golden City | Jason Felix | Blue | C | Rivals of Ixalan |
| 20 | Security Blockade | James Ryman | White | U | Return to Ravnica |
| 177 | Sedge Sliver | Richard Kane Ferguson | Red | R | Time Spiral |
| 187 | Sedge Sliver | Richard Kane Ferguson | Red | R | Time Spiral Remastered |
| Sedge Troll | Dan Frazier | Red | R | Revised Edition |
| Sedge Troll | Dan Frazier | Red | R | Unlimited Edition |
| Sedge Troll | Dan Frazier | Red | R | Limited Edition Beta |
| Sedge Troll | Jeff A. Menges | Red | R | Limited Edition Alpha |
| 135 | Sedge Troll | Dan Frazier | Red | R | Masters Edition IV |
| 86 | Sedgemoor Witch | Igor Kieryluk | Black | R | Strixhaven: School of Mages |
| 306 | Sedgemoor Witch | Igor Kieryluk | Black | R | Strixhaven: School of Mages |
| 54 | Sedraxis Alchemist | Karl Kopinski | Black | C | Conflux |
| 181 | Sedraxis Specter | Cole Eastburn | Blue/Black/Red | U | Modern Masters 2017 Edition |
| 192 | Sedraxis Specter | Cole Eastburn | Blue/Black/Red | R | Shards of Alara |
| 273 | Sedraxis Specter | Cole Eastburn | Blue/Black/Red | U | Double Masters 2022 |
| 325 | Seedpod Caretaker | Slawomir Maniak | White | U | March of the Machine |
| Seeds of Innocence | Junior Tomlin | Green | R | Mirage |
| 98 | Seek Bolas's Counsel (playtest) | Matt Warren | Blue/Black/Red | C | Mystery Booster |
| 220 | Seek Thrills | Victor Adame Minguez | Blue/Red/Green | M | Wilds of Eldraine |
| 285 | Seek Thrills | Kev Walker | Blue/Red/Green | M | Wilds of Eldraine |
| 330 | Seer of Stolen Sight | Betty Jiang | Black | U | March of the Machine |
| 44 | Seer of the Last Tomorrow | Sara Winters | Blue | C | Hour of Devastation |
| 77 | Seer of the Last Tomorrow | Sara Winters | Blue | C | Amonkhet Remastered |
| 165 | Seer's Lantern | Jung Park | | C | Oath of the Gatewatch |
| 220 | Seer's Lantern | Jung Park | | C | Commander 2018 |
| 245 | Seer's Lantern | Jung Park | | C | Battlebond |
| 338 | Seer's Lantern | Jung Park | | C | Commander Legends |
| 101 | Seething Pathblazer | Steve Prescott | Red | C | Morningtide |
| 46 | Seething Song | Martina Pilcerova | Red | C | Archenemy |
| 70 | Seething Song | Jaime Jones | Red | C | Duel Decks: Knights vs. Dragons |
| 104 | Seething Song | Martina Pilcerova | Red | C | Mirrodin |
| 179 | Seething Song | Martina Pilcerova | Red | C | Commander 2021 |
| 216 | Seething Song | Martina Pilcerova | Red | C | Ninth Edition |
| 3 | Sefris of the Hidden Ways | Ryan Pancoast | White/Blue/Black | M | Adventures in the Forgotten Realms Commander |
| 326 | Sefris of the Hidden Ways | Ryan Pancoast | White/Blue/Black | M | Adventures in the Forgotten Realms Commander |
| 101 | Seismic Assault | Dermot Power | Red | R | Exodus |
| 146 | Seismic Assault | Adam Paquette | Red | R | Ultimate Masters |
| 216 | Seismic Assault | Greg Staples | Red | R | Seventh Edition |
| 219 | Seismic Assault | Greg Staples | Red | R | Eighth Edition |
| 228 | Seismic Assault | Greg Staples | Red | R | Tenth Edition |
| 156 | Seismic Rupture | Jason A. Engle | Red | U | Dragons of Tarkir |
| 70 | Seismic Strike | Christopher Moeller | Red | C | Duel Decks: Venser vs. Koth |
| 71 | Seismic Strike | Christopher Moeller | Red | C | Duel Decks: Knights vs. Dragons |
| 154 | Seismic Strike | Christopher Moeller | Red | C | Magic 2010 |
| 280 | Seismic Strike | Christopher Moeller | Red | C | Magic 2015 Core Set |
| 161 | Seismic Wave | Aaron J. Riley | Red | U | Kamigawa: Neon Dynasty |
| 64 | Seize the Secrets | Miranda Meeks | Blue | C | Outlaws of Thunder Junction |
| 86 | Seize the Spoils | Jesper Ejsing | Red | C | Game Night: Free-For-All |
| 149 | Seize the Spoils | Jesper Ejsing | Red | C | Kaldheim |
| 52 | Seize the Spotlight | Ernanda Souza | Red | R | Streets of New Capenna Commander |
| 152 | Seize the Spotlight | Ernanda Souza | Red | R | Streets of New Capenna Commander |
| 179 | Seize the Spotlight | Ernanda Souza | Red | R | Outlaws of Thunder Junction Commander |
| 144 | Selesnya Cluestone | Raoul Vitale | | C | Dragon's Maze |
| 35 | Selesnya Eulogist | Tomasz Jedruszek | Green | R | Commander 2019 |
| 233 | Selesnya Keyrune | Daniel Ljunggren | | U | Return to Ravnica |
| 240 | Selesnya Locket | Winona Nelson | | C | Guilds of Ravnica |
| 21 | Selesnya Sentry | Wesley Burt | White | C | Return to Ravnica |
| 157 | Selfless Glyphweaver | Johannes Voss | White | R | Strixhaven: School of Mages |
| 329 | Selfless Glyphweaver | Johannes Voss | White | R | Strixhaven: School of Mages |
| 21 | Selhoff Occultist | Igor Kieryluk | Blue | C | Shadows of the Past |
| 73 | Selhoff Occultist | Igor Kieryluk | Blue | C | Innistrad |
| 174 | Selhoff Occultist | Igor Kieryluk | Blue | C | Jumpstart |
| 158 | Selkie Hedge-Mage | Larry MacDougall | Blue/Green | U | Eventide |
| 22 | Seller of Songbirds | Christopher Moeller | White | C | Return to Ravnica |
| 72 | Seller of Songbirds | Christopher Moeller | White | C | Ravnica Clue Edition |
| 240 | Seller of Songbirds | Christopher Moeller | White | C | Jumpstart 2022 |
| 51 | Selvala, Explorer Returned | Tyler Jacobson | White/Green | R | Magic: The Gathering—Conspiracy |
| 167 | Selvala, Explorer Returned | Tyler Jacobson | White/Green | R | Dominaria United Commander |
| 218 | Selvala, Explorer Returned | Tyler Jacobson | White/Green | R | Murders at Karlov Manor Commander |
| 220 | Selvala, Explorer Returned | Tyler Jacobson | White/Green | R | Commander 2016 |
| 260 | Selvala, Explorer Returned | Tyler Jacobson | White/Green | R | Vintage Masters |
| 350 | Selvala, Explorer Returned | Tyler Jacobson | White/Green | R | Streets of New Capenna Commander |
| 70 | Selvala, Heart of the Wilds | Tyler Jacobson | Green | M | Conspiracy: Take the Crown |
| 246 | Selvala, Heart of the Wilds | Tyler Jacobson | Green | M | Modern Horizons 3 Commander |
| 320 | Selvala, Heart of the Wilds | Tyler Jacobson | Green | M | Commander Masters |
| 429 | Selvala, Heart of the Wilds | Tyler Jacobson | Green | M | Jumpstart |
| 571 | Selvala, Heart of the Wilds | Tyler Jacobson | Green | M | Commander Masters |
| 681 | Selvala, Heart of the Wilds | Jack Hughes | Green | M | Commander Masters |
| 1064 | Selvala, Heart of the Wilds | Jack Hughes | Green | M | Commander Masters |
| 52 | Semblance Anvil | Dan Scott | | R | The Brothers' War Retro Artifacts |
| 115 | Semblance Anvil | Dan Scott | | R | The Brothers' War Retro Artifacts |
| 201 | Semblance Anvil | Dan Scott | | R | Scars of Mirrodin |
| 9 | Semblance Scanner | Leonardo Santanna | Blue | R | Kamigawa: Neon Dynasty Alchemy |
| 50 | Senate Courier | Johann Bodin | Blue | C | Ravnica Allegiance |
| Sengir Bats | Dan Frazier | Black | C | Homelands |
| Sengir Bats | Dan Frazier | Black | C | Homelands |
| 102 | Sensation Gorger | Matt Cavotta | Red | R | Morningtide |
| 184 | Sentinel of Lost Lore | Cristi Balanescu | Green | R | Wilds of Eldraine |
| 358 | Sentinel of Lost Lore | Cristi Balanescu | Green | R | Wilds of Eldraine |
| 211 | Sentinel of the Nameless City | Josu Hernaiz | Green | R | The Lost Caverns of Ixalan |
| 383 | Sentinel of the Nameless City | Josu Hernaiz | Green | R | The Lost Caverns of Ixalan |
| 55 | Septic Rats | Cos Koniotis | Black | U | Mirrodin Besieged |
| 67 | Sequence Engine | Aaron Miller | Green | R | Commander 2021 |
| 394 | Sequence Engine | Aaron Miller | Green | R | Commander 2021 |
| 36 | Seraph of New Capenna | Aaron J. Riley | White | U | March of the Machine |
| Serendib Efreet | Jesper Myrfors | Blue | R | Revised Edition |
| Serendib Efreet | Anson Maddocks | Blue | R | Arabian Nights |
| 11 | Serendib Efreet | Matt Stewart | Blue | M | From the Vault: Exiled |
| 50 | Serendib Efreet | Anson Maddocks | Blue | R | Masters Edition |
| 70 | Serendib Efreet | Matt Stewart | Blue | R | Eternal Masters |
| 93 | Serendib Efreet | Matt Stewart | Blue | U | Vintage Masters |
| 175 | Serendib Efreet | Matt Stewart | Blue | R | Jumpstart |
| 61 | Serendib Sorcerer | Dan Scott | Blue | R | Planar Chaos |
| 93 | Serendib Sorcerer | Dan Scott | Blue | R | Commander 2017 |
| 157 | Sergeant John Benton | Wei Guan | White/Green | R | Doctor Who Commander |
| 441 | Sergeant John Benton | Wei Guan | White/Green | R | Doctor Who Commander |
| 32 | Sergeant-at-Arms | Scott Murphy | White | C | Dominaria |
| 240 | Serpent Skin | Rob Alexander | Green | C | Champions of Kamigawa |
| Serpent Warrior | Ron Spencer | Black | C | Stronghold |
| Serpent Warrior | Roger Raupp | Black | C | Portal |
| 88 | Serpent Warrior | Ron Spencer | Black | C | Starter 1999 |
| 117 | Serpent Warrior | Ron Spencer | Black | C | Tempest Remastered |
| 161 | Serpent Warrior | Ron Spencer | Black | C | Eighth Edition |
| 162 | Serpent Warrior | Ron Spencer | Black | C | Ninth Edition |
| 162 | Serpent Warrior | Eric Peterson | Black | C | Seventh Edition |
| 205 | Serpent-Blade Assailant | Durion | Green | C | March of the Machine |
| 190 | Serpent's Gift | Steve Argyle | Green | C | Magic 2013 |
| 11 | Serpent's Soul-Jar | Dan Scott | Black | R | Kaldheim Commander |
| 17 | Serra's Boon | Steven Belledin | White | U | Planar Chaos |
| 18 | Serra's Boon | Steven Belledin | White | U | Duel Decks Anthology, Divine vs. Demonic |
| 18 | Serra's Boon | Steven Belledin | White | U | Duel Decks: Divine vs. Demonic |
| Serrated Biskelion | Ron Spencer | | U | Weatherlight |
| 46 | Serrated Biskelion | Ron Spencer | | U | Duel Decks: Elspeth vs. Tezzeret |
| 138 | Serum Powder | Matt Thompson | | R | Darksteel |
| 228 | Serum Powder | Matt Thompson | | R | Iconic Masters |