| 59 | Epiphany at the Drownyard | Titus Lunter | Blue | R | Shadows over Innistrad |
| 65 | Epiphany at the Drownyard | Titus Lunter | Blue | R | Shadows Over Innistrad Remastered |
| 91 | Epiphany Storm | Clint Cearley | Red | C | Born of the Gods |
| 118 | Epistolary Librarian | Games Workshop | White/Blue | R | Warhammer 40,000 Commander |
| 230 | Epitaph Golem | Adam Paquette | | U | Core Set 2021 |
| 249 | Epitaph Golem | Adam Paquette | | C | Shadows Over Innistrad Remastered |
| 254 | Epitaph Golem | Adam Paquette | | U | Shadows over Innistrad |
| 162 | Epochrasite | Michael Bruinsma | | R | Future Sight |
| 187 | Epochrasite | Michael Bruinsma | | R | Commander Anthology 2018 |
| 205 | Epochrasite | Michael Bruinsma | | U | Modern Masters |
| 238 | Epochrasite | Michael Bruinsma | | R | Commander 2014 |
| 4 | Equal Treatment | Greg & Tim Hildebrandt | White | U | Torment |
| 204 | Equestrian Skill | Zoltan Boros | Green | C | Shadows over Innistrad |
| 32 | Equilibrium | Jeff Miracola | Blue | R | Exodus |
| 71 | Equilibrium | Don Hazeltine | Blue | R | Seventh Edition |
| Equinox | Susan Van Camp | White | C | Legends |
| Equipoise | Adam Rex | White | R | Visions |
| 11 | Era of Enlightenment | アマヤギ堂/AMAYAGIDO | White | C | Kamigawa: Neon Dynasty |
| 45 | Era of Innovation | Jason Rainville | Blue | U | Kaladesh |
| 47 | Era of Innovation | Jason Rainville | Blue | U | Kaladesh Remastered |
| 183 | Era of Innovation | Jason Rainville | Blue | U | Modern Horizons 3 Commander |
| 60 | Eradicate | Kev Walker | Black | U | Urza's Destiny |
| 65 | Eradicate | Glen Angus | Black | U | Betrayers of Kamigawa |
| 94 | Eradicator Valkyrie | Tyler Jacobson | Black | M | Kaldheim |
| 353 | Eradicator Valkyrie | Tyler Jacobson | Black | M | Kaldheim |
| 7 | Erase | Ron Spears | White | C | Urza's Legacy |
| 9 | Erase | Zack Stella | White | C | Khans of Tarkir |
| 13 | Erase | Richard Wright | White | C | Magic 2013 |
| 10 | Erase (Not the Urza's Legacy One) | Pete "Yes the Urza's Legacy One" Venters | White | C | Unhinged |
| 35 | Erayo, Soratami Ascendant | Matt Cavotta | Blue | R | Saviors of Kamigawa |
| 35 | Erayo's Essence | Matt Cavotta | Blue | R | Saviors of Kamigawa |
| 60 | Erdwal Illuminator | Seb McKinnon | Blue | U | Shadows over Innistrad |
| 66 | Erdwal Illuminator | Seb McKinnon | Blue | U | Shadows Over Innistrad Remastered |
| 104 | Erdwal Illuminator | Erikas Perl | Blue | U | Murders at Karlov Manor Commander |
| 291 | Erdwal Illuminator | Seb McKinnon | Blue | U | Jumpstart 2022 |
| 86 | Erdwal Ripper | Kev Walker | Red | C | Dark Ascension |
| 122 | Erebor Flamesmith | L J Koh | Red | C | The Lord of the Rings: Tales of Middle Earth |
| 573 | Erebor Flamesmith | L J Koh | Red | C | The Lord of the Rings: Tales of Middle Earth |
| 93 | Erebos, Bleak-Hearted | Chase Stone | Black | M | Theros Beyond Death |
| 868 | Erebos, Bleak-Hearted | Chase Stone | Black | M | Commander Masters |
| 74 | Erebos, God of the Dead | Jason A. Engle | Black | M | Secret Lair Drop |
| 85 | Erebos, God of the Dead | Peter Mohrbacher | Black | M | Theros |
| 86 | Erebos's Emissary | Sam Burley | Black | U | Theros |
| 94 | Erebos's Intervention | Mathias Kollros | Black | R | Theros Beyond Death |
| 94 | Erebos's Titan | Peter Mohrbacher | Black | M | Magic Origins |
| 53 | Erestor of the Council | Syd Mills | Blue/Green | R | The Lord of the Rings: Tales of Middle Earth Commander |
| 136 | Erestor of the Council | Syd Mills | Blue/Green | R | The Lord of the Rings: Tales of Middle Earth Commander |
| 457 | Erestor of the Council | Syd Mills | Blue/Green | R | The Lord of the Rings: Tales of Middle Earth Commander |
| Erg Raiders | Stuart Griffin | Black | C | Fifth Edition |
| Erg Raiders | Dameon Willich | Black | C | Fourth Edition |
| Erg Raiders | Dameon Willich | Black | C | Revised Edition |
| Erg Raiders | Dameon Willich | Black | C | Arabian Nights |
| Erg Raiders | Dameon Willich | Black | C | Arabian Nights |
| 68 | Erg Raiders | Dameon Willich | Black | C | Masters Edition |
| 90 | Erg Raiders | Kev Walker | Black | C | Masters 25 |
| Erhnam Djinn | Dave Dorman | Green | U | Beatdown Box Set |
| Erhnam Djinn | Ken Meyer, Jr. | Green | U | Chronicles |
| Erhnam Djinn | Ken Meyer Jr. | Green | R | Arabian Nights |
| 113 | Erhnam Djinn | Greg Staples | Green | R | Judgment |
| 207 | Erhnam Djinn | Greg Staples | Green | U | Vintage Masters |
| 202 | Eriette of the Charmed Apple | Magali Villeneuve | White/Black | M | Wilds of Eldraine |
| 299 | Eriette of the Charmed Apple | Zach Alexander | White/Black | M | Wilds of Eldraine |
| 202 | Eriette, the Beguiler | Chris Rallis | White/Blue/Black | R | Outlaws of Thunder Junction |
| 293 | Eriette, the Beguiler | Dibujante Nocturno | White/Blue/Black | R | Outlaws of Thunder Junction |
| 10 | Eriette's Lullaby | Anton Solovianchyk | White | C | Outlaws of Thunder Junction |
| 245 | Eriette's Tempting Apple | Alayna Danner | | U | Wilds of Eldraine |
| 88 | Eriette's Whisper | Quintin Gleim | Black | C | Wilds of Eldraine |
| 230 | Erinis, Gloom Stalker | Ioannis Fiore | Green | U | Commander Legends: Battle for Baldur's Gate |
| 407 | Erinis, Gloom Stalker | Jeff Dee | Green | U | Commander Legends: Battle for Baldur's Gate |
| 5 | Eris, Roar of the Storm | Aurore Folny | Blue/Red | M | Outlaws of Thunder Junction Commander |
| 41 | Eris, Roar of the Storm | Aurore Folny | Blue/Red | M | Outlaws of Thunder Junction Commander |
| 244 | Erithizon | Scott M. Fischer | Green | R | Mercadian Masques |
| 123 | Erkenbrand, Lord of Westfold | Alexander Mokhov | Red | U | The Lord of the Rings: Tales of Middle Earth |
| 574 | Erkenbrand, Lord of Westfold | Alexander Mokhov | Red | U | The Lord of the Rings: Tales of Middle Earth |
| 256 | Eroded Canyon | Piotr Dura | | L | Outlaws of Thunder Junction |
| Eron the Relentless | Christopher Rush | Red | U | Homelands |
| 61 | Eron the Relentless | Christopher Rush | Red | S | Time Spiral "Timeshifted" |
| Erosion | Pete Venters | Blue | C | Fourth Edition |
| Erosion | Pete Venters | Blue | C | The Dark |
| Errand of Duty | Julie Baroh | White | C | Alliances |
| Errand of Duty | Julie Baroh | White | C | Alliances |
| 12 | Errand of Duty | Julie Baroh | White | U | Masters Edition II |
| 11 | Errand-Rider of Gondor | YW Tang | White | C | The Lord of the Rings: Tales of Middle Earth |
| 462 | Errand-Rider of Gondor | YW Tang | White | C | The Lord of the Rings: Tales of Middle Earth |
| 224 | Errant and Giada | Cristi Balanescu | White/Blue | R | March of the Machine |
| 306 | Errant and Giada | Shawn Pagels | White/Blue | R | March of the Machine |
| 15 | Errant Doomsayers | Liz Danforth | White | C | Time Spiral |
| 17 | Errant Doomsayers | Liz Danforth | White | C | Time Spiral Remastered |
| 20 | Errant Ephemeron | Luca Zontini | Blue | C | Duel Decks Anthology, Jace vs. Chandra |
| 20 | Errant Ephemeron | Luca Zontini | Blue | C | Duel Decks: Jace vs. Vraska |
| 20 | Errant Ephemeron | Luca Zontini | Blue | C | Duel Decks: Jace vs. Chandra |
| 41 | Errant Ephemeron | Luca Zontini | Blue | C | Modern Masters |
| 60 | Errant Ephemeron | Luca Zontini | Blue | C | Time Spiral |
| 66 | Errant Ephemeron | Luca Zontini | Blue | C | Time Spiral Remastered |
| Errant Minion | Harold McNeill | Blue | C | Ice Age |
| 41 | Errant, Street Artist | Justine Cruz | Blue | R | Streets of New Capenna |
| 344 | Errant, Street Artist | Alix Branwyn | Blue | R | Streets of New Capenna |
| Errantry | Scott Kirschner | Red | C | Fifth Edition |
| Errantry | L. A. Williams | Red | C | Ice Age |
| 124 | Errantry | Scott Kirschner | Red | C | Masters Edition II |
| 54 | Erratic Apparition | Miranda Meeks | Blue | C | Duskmourn: House of Horror |
| 98 | Erratic Cyclops | Milivoj Ćeran | Red | R | Guilds of Ravnica |
| 166 | Erratic Cyclops | Milivoj Ćeran | Red | R | Commander 2021 |
| 41 | Erratic Explosion | Gary Ruddell | Red | C | Planechase Anthology |
| 41 | Erratic Explosion | Gary Ruddell | Red | C | Planechase 2012 Edition |
| 201 | Erratic Explosion | Gary Ruddell | Red | C | Onslaught |
| 41 | Erratic Mutation | Zoltan Boros & Gabor Szikszai | Blue | C | Planar Chaos |
| 42 | Erratic Mutation | Zoltan Boros & Gabor Szikszai | Blue | C | Modern Masters |
| 67 | Erratic Mutation | Zoltan Boros & Gabor Szikszai | Blue | C | Time Spiral Remastered |
| 132 | Erratic Portal | John Matson | | R | Exodus |
| 222 | Erratic Portal | John Matson | | R | Tempest Remastered |
| 48 | Erratic Visionary | Randy Vargas | Blue | C | War of the Spark |
| 85 | Erratic Visionary | Randy Vargas | Blue | C | Ravnica Clue Edition |
| 150 | Erratic Visionary | Randy Vargas | Blue | C | Jumpstart |
| 158 | Error | Ron Spears & Wayne Reynolds | Blue/Black | U | Dissension |
| 239 | Error | Ron Spears & Wayne Reynolds | Blue/Black | U | Commander 2016 |
| Ersatz Gnomes | Ron Spencer | | U | Mirage |
| 169 | Erstwhile Trooper | Jason A. Engle | Black/Green | C | Guilds of Ravnica |
| 199 | Ertai Resurrected | Ryan Pancoast | Blue/Black | R | Dominaria United |
| 298 | Ertai Resurrected | Justin & Alexis Hernandez | Blue/Black | R | Dominaria United |
| 339 | Ertai Resurrected | Justin & Alexis Hernandez | Blue/Black | R | Dominaria United |
| 107 | Ertai, the Corrupted | Kev Walker | White/Blue/Black | R | Planeshift |
| 107 | Ertai, the Corrupted | Mark Tedin | White/Blue/Black | R | Planeshift |
| 33 | Ertai, Wizard Adept | Terese Nielsen | Blue | R | Exodus |
| Ertai's Familiar | Kipling West | Blue | R | Weatherlight |
| Ertai's Meddling | Steve Luke | Blue | R | Tempest |
| 48 | Ertai's Scorn | Alex Negrea | Blue | U | Dominaria United |
| 24 | Ertai's Trickery | Kev Walker | Blue | U | Planeshift |
| 203 | Ertha Jo, Frontier Mentor | Michal Ivan | White/Red | U | Outlaws of Thunder Junction |
| 142 | Erupting Dreadwolf | Zack Stella | | U | Eldritch Moon |
| 237 | Eruth, Tormented Prophet | Ekaterina Burmak | Blue/Red | R | Innistrad: Crimson Vow |
| 323 | Eruth, Tormented Prophet | Paul Jackson | Blue/Red | R | Innistrad: Crimson Vow |
| 342 | Eruth, Tormented Prophet | Dave Kendall | Blue/Red | R | Innistrad: Crimson Vow |
| 84 | Escape Artist | Scott M. Fischer | Blue | C | Odyssey |
| 18 | Escape Detection | Justyna Dura | Blue | U | Assassin's Creed |
| 191 | Escape Detection | Justyna Dura | Blue | U | Assassin's Creed |
| 12 | Escape from Orthanc | Anthony Devine | White | C | The Lord of the Rings: Tales of Middle Earth |
| 463 | Escape from Orthanc | Anthony Devine | White | C | The Lord of the Rings: Tales of Middle Earth |
| 48 | Escape Protocol | Deruchenko Alexander | Blue | U | Ikoria: Lair of Behemoths |
| 25 | Escape Routes | Marc Fishman | Blue | C | Planeshift |
| 189 | Escape to the Wilds | Chris Ostrowski | Red/Green | R | Throne of Eldraine |
| 223 | Escape to the Wilds | Chris Ostrowski | Red/Green | R | Outlaws of Thunder Junction Commander |
| 843 | Escape to the Wilds | Chris Ostrowski | Red/Green | R | Commander Legends: Battle for Baldur's Gate |
| 261 | Escape Tunnel | Carlos Palma Cruchaga | | C | Murders at Karlov Manor |
| 132 | Escape Velocity | Mathias Kollros | Red | U | Theros Beyond Death |
| 48 | Escaped Experiment | Billy Christian | Blue | C | Phyrexia: All Will Be One |
| 109 | Escaped Null | Ryan Pancoast | Black | U | Rise of the Eldrazi |
| Escaped Shapeshifter | Douglas Shuler | Blue | R | Tempest |
| 278 | Escarpment Fortress | Vaigintas Pakenis | White | R | Assassin's Creed |
| 168 | Esika, God of the Tree | Johannes Voss | Green | M | Kaldheim |
| 314 | Esika, God of the Tree | Collin Estrada | Green | M | Kaldheim |
| 169 | Esika's Chariot | Raoul Vitale | Green | R | Kaldheim |
| 215 | Esika's Chariot | Raoul Vitale | Green | R | Bloomburrow Commander |
| 315 | Esika's Chariot | WolfSkullJack | Green | R | Kaldheim |
| 67 | Esior, Wardwing Familiar | Jesper Ejsing | Blue | U | Commander Legends |
| 557 | Esior, Wardwing Familiar | Jesper Ejsing | Blue | U | Commander Legends |
| 10 | Esix, Fractal Bloom | Chase Stone | Blue/Green | M | Commander 2021 |
| 210 | Esix, Fractal Bloom | Chase Stone | Blue/Green | M | Murders at Karlov Manor Commander |
| 337 | Esix, Fractal Bloom | Chase Stone | Blue/Green | M | Commander 2021 |
| 5 | Esoteric Duplicator | Anton Solovianchyk | Blue | M | Outlaws of Thunder Junction: The Big Score |
| 35 | Esoteric Duplicator | Ben Hill | Blue | M | Outlaws of Thunder Junction: The Big Score |
| 70 | Esoteric Duplicator | Anton Solovianchyk | Blue | M | Outlaws of Thunder Junction: The Big Score |
| 40 | Esper Battlemage | Matt Cavotta | Blue | U | Shards of Alara |
| 167 | Esper Charm | Michael Bruinsma | White/Blue/Black | U | Shards of Alara |
| 179 | Esper Charm | Michael Bruinsma | White/Blue/Black | U | Commander 2018 |
| 105 | Esper Cormorants | Warren Mahy | White/Blue | C | Conflux |
| 223 | Esper Panorama | Franz Vohwinkel | | C | Shards of Alara |
| 235 | Esper Panorama | Franz Vohwinkel | | C | Adventures in the Forgotten Realms Commander |
| 286 | Esper Panorama | Franz Vohwinkel | | C | Commander 2013 Edition |
| 399 | Esper Panorama | Franz Vohwinkel | | C | Streets of New Capenna Commander |
| 12 | Esper Sentinel | Eric Deschamps | White | R | Modern Horizons 2 |
| 328 | Esper Sentinel | Eric Deschamps | White | R | Modern Horizons 2 |
| 107 | Esper Sojourners | John Avon | White/Blue/Black | C | Alara Reborn |
| 132 | Esper Stormblade | Matt Stewart | White/Blue/Black | C | Alara Reborn |
| 25 | Esperzoa | Warren Mahy | Blue | U | Conflux |
| 43 | Esperzoa | Warren Mahy | Blue | U | Modern Masters |
| 47 | Esperzoa | Warren Mahy | Blue | U | Duel Decks: Elspeth vs. Tezzeret |
| 49 | Esperzoa | Warren Mahy | Blue | U | Double Masters |
| 13 | Esquire of the King | Tyukina Tatiana | White | C | The Lord of the Rings: Tales of Middle Earth |
| 464 | Esquire of the King | Tyukina Tatiana | White | C | The Lord of the Rings: Tales of Middle Earth |
| 160 | Essence Backlash | Jung Park | Blue/Red | C | Return to Ravnica |
| Essence Bottle | Donato Giancola | | U | Tempest |
| 10 | Essence Capture | Adam Volker | Blue | U | Outlaws of Thunder Junction Breaking News |
| 37 | Essence Capture | Mathias Kollros | Blue | U | Ravnica Allegiance |
| 52 | Essence Capture | Campbell White | Blue | U | Kamigawa: Neon Dynasty |
| 12 | Essence Channeler | Wylie Beckert | White | R | Bloomburrow |
| 356 | Essence Channeler | Wylie Beckert | White | R | Bloomburrow |
| 69 | Essence Depleter | Chase Stone | Black | U | Oath of the Gatewatch |
| 43 | Essence Drain | Tony Szczudlo | Black | C | Darksteel |
| 93 | Essence Drain | Jim Nelson | Black | C | Magic 2013 |
| 141 | Essence Drain | Jim Nelson | Black | C | Tenth Edition |