| 280 | Okina, Temple to the Grandfathers | Keith Garletts | | R | Champions of Kamigawa |
| 309 | Oko, the Trickster | Chris Rallis | Blue/Green | M | Throne of Eldraine |
| 50 | Oko, Thief of Crowns | Michael Walsh | Blue/Green | M | Outlaws of Thunder Junction Breaking News |
| 77 | Oko, Thief of Crowns | Michael Walsh | Blue/Green | M | Outlaws of Thunder Junction Breaking News |
| 197 | Oko, Thief of Crowns | Yongjae Choi | Blue/Green | M | Throne of Eldraine |
| 310 | Oko's Accomplices | Zezhou Chen | Blue | C | Throne of Eldraine |
| 312 | Oko's Hospitality | Deruchenko Alexander | Blue/Green | R | Throne of Eldraine |
| 233 | Olag, Ludevic's Hubris | Ryan Pancoast | Blue/Black | R | Innistrad: Midnight Hunt |
| 320 | Olag, Ludevic's Hubris | Milivoj Ćeran | Blue/Black | R | Innistrad: Midnight Hunt |
| 232 | Old Ghastbark | Thomas M. Baxa | White/Green | C | Shadowmoor |
| Old Man of the Sea | Susan Van Camp | Blue | R | Arabian Nights |
| 45 | Old Man of the Sea | Susan Van Camp | Blue | R | Masters Edition III |
| 244 | Old Rutstein | Greg Staples | Black/Green | R | Innistrad: Crimson Vow |
| 326 | Old Rutstein | Mark Riddick | Black/Green | R | Innistrad: Crimson Vow |
| 227 | Old Stickfingers | Jehan Choo | Black/Green | R | Duskmourn: House of Horror Commander |
| 234 | Old Stickfingers | Jehan Choo | Black/Green | R | Innistrad: Midnight Hunt |
| 321 | Old Stickfingers | DZO | Black/Green | R | Innistrad: Midnight Hunt |
| 62 | Old-Fashioned Vampire | Simon Dominic | Black | U | Unstable |
| 199 | Old-Growth Dryads | Yongjae Choi | Green | R | Ixalan |
| 245 | Olivia, Crimson Bride | Anna Steinbauer | Black/Red | M | Innistrad: Crimson Vow |
| 315 | Olivia, Crimson Bride | Xiaobotong | Black/Red | M | Innistrad: Crimson Vow |
| 343 | Olivia, Crimson Bride | Bastien L. Deharme | Black/Red | M | Innistrad: Crimson Vow |
| 172 | Olivia's Attendants | Dmitry Burmak | Red | R | Innistrad: Crimson Vow |
| 307 | Olivia's Attendants | Christian Angel | Red | R | Innistrad: Crimson Vow |
| 127 | Olivia's Bloodsworn | Daarken | Black | U | Shadows Over Innistrad Remastered |
| 127 | Olivia's Bloodsworn | Daarken | Black | U | Shadows over Innistrad |
| 100 | Olivia's Dragoon | Chris Rallis | Black | C | Eldritch Moon |
| 109 | Olivia's Dragoon | Chris Rallis | Black | C | Ultimate Masters |
| 128 | Olivia's Dragoon | Chris Rallis | Black | C | Shadows Over Innistrad Remastered |
| 118 | Olivia's Midnight Ambush | Chris Rallis | Black | C | Innistrad: Midnight Hunt |
| 20 | Olivia's Wrath | Nestor Ossandon Leal | Black | R | Innistrad: Crimson Vow Commander |
| 58 | Olivia's Wrath | Nestor Ossandon Leal | Black | R | Innistrad: Crimson Vow Commander |
| 205 | Olivia's Wrath | Néstor Ossandón Leal | Black | R | The Lost Caverns of Ixalan Commander |
| 27 | Ollenbock Escort | Eric Wilkerson | White | U | Innistrad: Crimson Vow |
| 140 | Olog-hai Crusher | Andrea Piparo | Red | C | The Lord of the Rings: Tales of Middle Earth |
| 591 | Olog-hai Crusher | Andrea Piparo | Red | C | The Lord of the Rings: Tales of Middle Earth |
| 503 | Olórin's Searing Light | Matt Stewart | White/Red | R | The Lord of the Rings: Tales of Middle Earth Commander |
| 203 | Oloro, Ageless Ascetic | Eric Deschamps | White/Blue/Black | M | Commander 2013 Edition |
| 27 | Oltec Archaeologists | Winona Nelson | White | C | The Lost Caverns of Ixalan |
| 708 | Omarthis, Ghostfire Initiate | Brent Hollowell | | M | Commander Masters |
| 748 | Omarthis, Ghostfire Initiate | Brent Hollowell | | M | Commander Masters |
| 58 | Omen of the Sea | Piotr Dura | Blue | C | Theros Beyond Death |
| 30 | Omen of the Sun | Piotr Dura | White | C | Theros Beyond Death |
| 831 | Omen of the Sun | Piotr Dura | White | C | Commander Masters |
| 39 | Omenspeaker | Dallas Williams | Blue | C | Duel Decks: Elspeth vs. Kiora |
| 57 | Omenspeaker | Dallas Williams | Blue | C | Theros |
| 64 | Omenspeaker | Dallas Williams | Blue | C | Core Set 2019 |
| 83 | Omenspeaker | Dallas Williams | Blue | C | Commander Legends |
| 118 | Omenspeaker | Dallas Williams | Blue | C | Conspiracy: Take the Crown |
| 125 | Omenspeaker | Dallas Williams | Blue | C | Battlebond |
| 189 | Ominous Cemetery | Anato Finnstark | | U | Doctor Who Commander |
| 241 | Ominous Parcel | Joe Slucher | | C | Streets of New Capenna |
| 65 | Ominous Roost | Josu Hernaiz | Blue | U | Innistrad: Midnight Hunt |
| 61 | Ominous Seas | Vincent Proce | Blue | U | Ikoria: Lair of Behemoths |
| 41 | Ominous Sphinx | Lars Grant-West | Blue | U | Hour of Devastation |
| 72 | Ominous Sphinx | Lars Grant-West | Blue | U | Amonkhet Remastered |
| 62 | Ominous Traveler | Igor Kieryluk | | R | Innistrad: Midnight Hunt Alchemy |
| 249 | Omnath, Locus of All | Bryan Sola | White/Blue/Black/Red/Green | R | March of the Machine |
| 313 | Omnath, Locus of All | Jessica Rossier | White/Blue/Black/Red/Green | R | March of the Machine |
| 387 | Omnath, Locus of All | Helge C. Balzer | White/Blue/Black/Red/Green | R | March of the Machine |
| 232 | Omnath, Locus of Creation | Chris Rahn | White/Blue/Red/Green | M | Zendikar Rising |
| 312 | Omnath, Locus of Creation | Bastien Grivet | White/Blue/Red/Green | M | Zendikar Rising |
| 2 | Omnath, Locus of Mana | Chase Stone | Green | M | Commander Collection: Green |
| 7 | Omnath, Locus of Mana | Mike Bierek | Green | M | From the Vault: Legends |
| 109 | Omnath, Locus of Mana | Mike Bierek | Green | M | Worldwake |
| 310 | Omnath, Locus of Mana | Mike Bierek | Green | M | Commander Masters |
| 568 | Omnath, Locus of Mana | Mike Bierek | Green | M | Commander Masters |
| 680 | Omnath, Locus of Mana | Alex Dos Diaz | Green | M | Commander Masters |
| 1063 | Omnath, Locus of Mana | Alex Dos Diaz | Green | M | Commander Masters |
| 97 | Omnath, Locus of Rage | Brad Rigney | Red/Green | M | Zendikar Rising Commander |
| 217 | Omnath, Locus of Rage | Brad Rigney | Red/Green | M | Battle for Zendikar |
| 236 | Omnath, Locus of Rage | Brad Rigney | Red/Green | M | Outlaws of Thunder Junction Commander |
| 216 | Omnath, Locus of the Roil | Lius Lasahido | Blue/Red/Green | M | Core Set 2020 |
| 116 | Omniclown Colossus | Ralph Horsley | Red | R | Unfinity (Acorn) |
| 24 | Omniscience | Justin & Alexis Hernandez | Blue | M | Wilds of Eldraine Enchanting Tales |
| 34 | Omniscience | Josh Hass | Blue | S | Masterpiece Series: Amonkhet Invocations |
| 63 | Omniscience | Jason Chan | Blue | M | Magic 2013 |
| 65 | Omniscience | Jason Chan | Blue | M | Core Set 2019 |
| 70 | Omniscience | やこたこす/YAKOTAKOS | Blue | M | Wilds of Eldraine Enchanting Tales |
| 49 | Omnispell Adept | Jason Rainville | Blue | R | Guilds of Ravnica |
| 192 | Omnivorous Flytrap | Antonio José Manzanedo | Green | R | Duskmourn: House of Horror |
| 322 | Omnivorous Flytrap | Chun Lo | Green | R | Duskmourn: House of Horror |
| 2 | Omo, Queen of Vesuva | Alex Brock | Blue/Green | M | Modern Horizons 3 Commander |
| 14 | Omo, Queen of Vesuva | Chun Lo | Blue/Green | M | Modern Horizons 3 Commander |
| 22 | Omo, Queen of Vesuva | Alex Brock | Blue/Green | M | Modern Horizons 3 Commander |
| 30 | Omo, Queen of Vesuva | Alex Brock | Blue/Green | M | Modern Horizons 3 Commander |
| 31 | On Alert | Lie Setiawan | White | C | Throne of Eldraine |
| 28 | On Serra's Wings | Johannes Voss | White | U | Dominaria |
| 380 | On Serra's Wings | Johannes Voss | White | U | Commander Legends |
| 30 | Ondu Inversion | James Paick | White | R | Zendikar Rising |
| 321 | Ondu Inversion | James Paick | White | R | Zendikar Rising |
| 196 | Ondu Knotmaster | Jarel Threat | White/Black | U | Modern Horizons 3 |
| 41 | Ondu Rising | Igor Kieryluk | White | U | Battle for Zendikar |
| 30 | Ondu Skyruins | James Paick | | R | Zendikar Rising |
| 321 | Ondu Skyruins | James Paick | | R | Zendikar Rising |
| 101 | Ondu Spiritdancer | Tran Nguyen | White | R | Duskmourn: House of Horror Commander |
| 723 | Ondu Spiritdancer | Tran Nguyen | White | R | Commander Masters |
| 756 | Ondu Spiritdancer | Tran Nguyen | White | R | Commander Masters |
| 126 | One Dozen Eyes | Darrell Riche | Green | U | Mirrodin |
| 159 | One Dozen Eyes | Darrell Riche | Green | U | Commander 2013 Edition |
| 22 | One Last Job | Caroline Gariba | White | R | Outlaws of Thunder Junction |
| 315 | One Last Job | Caroline Gariba | White | R | Outlaws of Thunder Junction |
| 41 | One Thousand Lashes | Daarken | White/Black | U | Guild Kit: Orzhov |
| 183 | One Thousand Lashes | Daarken | White/Black | U | Gatecrash |
| 45 | One with Death (playtest) | Robert Schuster | Black | C | Mystery Booster |
| 59 | One with the Multiverse | Liiga Smilshkalne | Blue | M | The Brothers' War |
| 121 | One with the Multiverse | Liiga Smilshkalne | Blue | M | Duskmourn: House of Horror Commander |
| 316 | One with the Multiverse | Liiga Smilshkalne | Blue | M | The Brothers' War |
| 59 | One with the Stars | Caio Monteiro | Blue | U | Theros Beyond Death |
| 230 | One-Eyed Scarecrow | Dave Kendall | | C | Innistrad |
| 77 | Ongoing Investigation | Bud Cook | Blue | U | Shadows over Innistrad |
| 84 | Ongoing Investigation | Bud Cook | Blue | U | Shadows Over Innistrad Remastered |
| 114 | Ongoing Investigation | Bud Cook | Blue | U | Murders at Karlov Manor Commander |
| 19 | Oni of Wild Places | Mark Tedin | Red | U | Duel Decks: Speed vs. Cunning |
| 85 | Oni of Wild Places | Mark Tedin | Red | U | Commander Anthology |
| 108 | Oni of Wild Places | Mark Tedin | Red | U | Saviors of Kamigawa |
| 130 | Oni of Wild Places | Mark Tedin | Red | U | Magic: The Gathering-Commander |
| 51 | Oni Possession | Aleksi Briclot | Black | U | Duel Decks Anthology, Divine vs. Demonic |
| 51 | Oni Possession | Aleksi Briclot | Black | U | Duel Decks: Divine vs. Demonic |
| 135 | Oni Possession | Aleksi Briclot | Black | U | Champions of Kamigawa |
| 92 | Onslaught | Paolo Parente | Red | C | Exodus |
| Onyx Talisman | Sandra Everingham | | U | Ice Age |
| 51 | Oona's Blackguard | Kev Walker | Black | U | Zendikar Rising Commander |
| 72 | Oona's Blackguard | Kev Walker | Black | U | Morningtide |
| 261 | Oona's Blackguard | Kev Walker | Black | U | Jumpstart |
| 173 | Oona's Gatewarden | Mike Dringenberg | Blue/Black | C | Shadowmoor |
| 27 | Oona's Grace | Rebecca Guay | Blue | C | Eventide |
| 63 | Oona's Grace | Rebecca Guay | Blue | C | Eternal Masters |
| 91 | Oona's Grace | Rebecca Guay | Blue | C | Commander 2019 |
| 85 | Oona's Prowler | Wayne Reynolds | Black | R | Double Masters 2022 |
| 133 | Oona's Prowler | Wayne Reynolds | Black | R | Lorwyn |
| 443 | Oona's Prowler | Wayne Reynolds | Black | R | Double Masters 2022 |
| 16 | Opal Lake Gatekeepers | Seb McKinnon | Blue | C | Dragon's Maze |
| 13 | Opalescence | John Avon | White | R | Urza's Destiny |
| 17 | Opal-Eye, Konda's Yojimbo | Greg Staples | White | R | Betrayers of Kamigawa |
| 141 | Opaline Bracers | Anthony S. Waters | | C | Fifth Dawn |
| 244 | Opaline Sliver | Dave Dorman | White/Blue | U | Time Spiral |
| 133 | Open the Gates | John Thacker | Green | C | Ravnica Allegiance |
| 151 | Open the Gates | John Thacker | Green | C | Ravnica Remastered |
| 112 | Open the Graves | Vincent Proce | Black | R | Core Set 2019 |
| 126 | Open the Graves | Vincent Proce | Black | R | Innistrad: Midnight Hunt Commander |
| 143 | Open the Omenpaths | Eric Deschamps | Red | C | Kaldheim |
| 21 | Open the Vaults | Brian Despain | White | R | Magic 2010 |
| 24 | Open the Vaults | Brian Despain | White | R | Double Masters |
| 72 | Open the Vaults | Brian Despain | White | R | Commander 2016 |
| 77 | Open the Vaults | Brian Despain | White | R | Commander 2015 |
| 168 | Open the Vaults | Ilker Yildiz | White | R | Magic The Gathering—Fallout |
| 455 | Open the Vaults | Ilker Yildiz | White | R | Magic The Gathering—Fallout |
| Opportunist | Dan Frazier | Red | U | Tempest |
| 133 | Opportunistic Dragon | Chris Rahn | Red | R | Throne of Eldraine |
| 134 | Opportunistic Dragon | Chris Rahn | Red | R | Adventures in the Forgotten Realms Commander |
| 35 | Opposition | Svetlin Velinov | Blue | S | Masterpiece Series: Amonkhet Invocations |
| 40 | Opposition | Todd Lockwood | Blue | R | Urza's Destiny |
| 62 | Opposition | Todd Lockwood | Blue | R | Dominaria Remastered |
| 92 | Opposition | Mark Brill | Blue | R | Seventh Edition |
| 290 | Opposition | Todd Lockwood | Blue | R | Dominaria Remastered |
| 141 | Opposition Agent | Scott Murphy | Black | R | Commander Legends |
| 651 | Opposition Agent | Scott Murphy | Black | R | Commander Legends |
| 32 | Oppression | Matteo Bassini | Black | R | Wilds of Eldraine Enchanting Tales |
| 143 | Oppression | Pete Venters | Black | R | Urza's Saga |
| 152 | Oppression | Alex Horley-Orlandelli | Black | R | Seventh Edition |
| 19 | Oppressive Rays | Mark Zug | White | C | Journey into Nyx |
| 21 | Oppressive Rays | Mark Zug | White | C | Magic 2015 Core Set |
| 50 | Oppressive Will | Pat Lee | Blue | C | Saviors of Kamigawa |
| 21 | Optimistic Scavenger | Brian Valeza | White | U | Duskmourn: House of Horror |
| 288 | Optimistic Scavenger | Brian Valeza | White | U | Duskmourn: House of Horror |
| 13 | Optimus Prime, Autobot Leader | Volta Creation | White/Blue/Red | M | The Brothers' War Transformers Cards |
| 27 | Optimus Prime, Autobot Leader | Volta Creation | White/Blue/Red | M | The Brothers' War Transformers Cards |
| 13 | Optimus Prime, Hero | Volta Creation | White/Blue/Red | M | The Brothers' War Transformers Cards |
| 27 | Optimus Prime, Hero | Volta Creation | White/Blue/Red | M | The Brothers' War Transformers Cards |
| 103 | Oracle of Bones | Greg Staples | Red | R | Born of the Gods |
| 63 | Oracle of Dust | Jason Rainville | Blue | C | Battle for Zendikar |
| 233 | Oracle of Nectars | Brandon Kitkouski | White/Green | R | Shadowmoor |
| 16 | Oracle's Attendants | Orizio Daniele | White | R | Nemesis |
| 30 | Oracle's Attendants | Dany Orizio | White | R | Ninth Edition |
| 32 | Oracle's Attendants | Dany Orizio | White | R | Eighth Edition |
| 47 | Oracle's Insight | Raymond Swanland | Blue | U | Born of the Gods |
| 127 | Oracle's Insight | Raymond Swanland | Blue | U | Battlebond |
| 234 | Oracle's Vault | Jonas De Ro | | R | Amonkhet |
| 374 | Oracle's Vault | Jonas De Ro | | R | Streets of New Capenna Commander |
| 233 | Orah, Skyclave Hierophant | Heonhwa Choe | White/Black | R | Zendikar Rising |
| 369 | Orah, Skyclave Hierophant | Heonhwa Choe | White/Black | R | Zendikar Rising |
| 54 | Oran-Rief Recluse | Lars Grant-West | Green | C | Duel Decks: Jace vs. Vraska |
| 173 | Oran-Rief Recluse | Lars Grant-West | Green | C | Zendikar |
| 174 | Oran-Rief Survivalist | Kev Walker | Green | C | Zendikar |
| 28 | Oran-Rief, the Vastwood | Mike Bierek | | R | Duel Decks: Elves vs. Inventors |
| 173 | Oran-Rief, the Vastwood | Mike Bierek | | R | Kamigawa: Neon Dynasty Commander |
| 221 | Oran-Rief, the Vastwood | Mike Bierek | | R | Zendikar |
| 263 | Oran-Rief, the Vastwood | Mike Bierek | | R | Commander Anthology |
| 296 | Oran-Rief, the Vastwood | Mike Bierek | | R | Ikoria Commander |
| 297 | Oran-Rief, the Vastwood | Mike Bierek | | R | Commander 2015 |
| 305 | Oran-Rief, the Vastwood | Mike Bierek | | R | Commander 2014 |
| 307 | Oran-Rief, the Vastwood | Mike Bierek | | R | Commander 2021 |
| 320 | Oran-Rief, the Vastwood | Mike Bierek | | R | Bloomburrow Commander |
| 156 | Orb of Dreams | Dany Orizio | | R | Betrayers of Kamigawa |
| 234 | Orbs of Warding | Johann Bodin | | R | Magic Origins |
| 78 | Orc Sureshot | Kev Walker | Black | U | Fate Reforged |
| 37 | Orca, Siege Demon | Daarken | Black/Red | R | Dominaria United Commander |
| 192 | Orchard Spirit | Howard Lyon | Green | C | Magic Origins |
| 198 | Orchard Spirit | Howard Lyon | Green | C | Innistrad |