| 126 | One Dozen Eyes | Darrell Riche | Green | U | Mirrodin |
| 159 | One Dozen Eyes | Darrell Riche | Green | U | Commander 2013 Edition |
| 22 | One Last Job | Caroline Gariba | White | R | Outlaws of Thunder Junction |
| 315 | One Last Job | Caroline Gariba | White | R | Outlaws of Thunder Junction |
| 229 | One of the Pack | Craig J Spearing | Green | C | Shadows over Innistrad |
| 102 | One Ring to Rule Them All | L J Koh | Black | R | The Lord of the Rings: Tales of Middle Earth |
| 553 | One Ring to Rule Them All | L J Koh | Black | R | The Lord of the Rings: Tales of Middle Earth |
| 41 | One Thousand Lashes | Daarken | White/Black | U | Guild Kit: Orzhov |
| 183 | One Thousand Lashes | Daarken | White/Black | U | Gatecrash |
| 45 | One with Death (playtest) | Robert Schuster | Black | C | Mystery Booster |
| 125 | One with Nature | Daren Bader | Green | U | Scourge |
| 84 | One with Nothing | Jim Nelson | Black | R | Saviors of Kamigawa |
| 27 | One with the Kami | Justyna Gil | Green | R | Kamigawa: Neon Dynasty Commander |
| 69 | One with the Kami | Justyna Gil | Green | R | Kamigawa: Neon Dynasty Commander |
| 66 | One with the Machine | Chase Stone | Blue | R | Core Set 2019 |
| 90 | One with the Machine | Chase Stone | Blue | R | The Brothers' War Commander |
| 179 | One with the Machine | Bartek Fedyczak | Blue | R | Magic The Gathering—Fallout |
| 462 | One with the Machine | Bartek Fedyczak | Blue | R | Magic The Gathering—Fallout |
| 59 | One with the Multiverse | Liiga Smilshkalne | Blue | M | The Brothers' War |
| 121 | One with the Multiverse | Liiga Smilshkalne | Blue | M | Duskmourn: House of Horror Commander |
| 316 | One with the Multiverse | Liiga Smilshkalne | Blue | M | The Brothers' War |
| 59 | One with the Stars | Caio Monteiro | Blue | U | Theros Beyond Death |
| 64 | One With the Wind | Naomi Baker | Blue | C | Ixalan |
| 330 | One With the Wind | Naomi Baker | Blue | C | Jumpstart 2022 |
| 117 | One-Clown Band | Ralph Horsley | Red | C | Unfinity |
| 230 | One-Eyed Scarecrow | Dave Kendall | | C | Innistrad |
| 60 | Oneirophage | Martina Pilcerova | Blue | U | Modern Horizons |
| 162 | Oneirophage | Martina Pilcerova | Blue | U | Jumpstart |
| 331 | Oneirophage | Martina Pilcerova | Blue | U | Jumpstart 2022 |
| 77 | Ongoing Investigation | Bud Cook | Blue | U | Shadows over Innistrad |
| 84 | Ongoing Investigation | Bud Cook | Blue | U | Shadows Over Innistrad Remastered |
| 114 | Ongoing Investigation | Bud Cook | Blue | U | Murders at Karlov Manor Commander |
| 19 | Oni of Wild Places | Mark Tedin | Red | U | Duel Decks: Speed vs. Cunning |
| 85 | Oni of Wild Places | Mark Tedin | Red | U | Commander Anthology |
| 108 | Oni of Wild Places | Mark Tedin | Red | U | Saviors of Kamigawa |
| 130 | Oni of Wild Places | Mark Tedin | Red | U | Magic: The Gathering-Commander |
| 51 | Oni Possession | Aleksi Briclot | Black | U | Duel Decks Anthology, Divine vs. Demonic |
| 51 | Oni Possession | Aleksi Briclot | Black | U | Duel Decks: Divine vs. Demonic |
| 135 | Oni Possession | Aleksi Briclot | Black | U | Champions of Kamigawa |
| 127 | Oni-Cult Anvil | Yeong-Hao Han | Black/Red | U | The Brothers' War Commander |
| 230 | Oni-Cult Anvil | Yeong-Hao Han | Black/Red | U | Kamigawa: Neon Dynasty |
| 92 | Onslaught | Paolo Parente | Red | C | Exodus |
| Onulet | Anson Maddocks | | R | Fourth Edition |
| Onulet | Kerstin Kaman | | R | Revised Edition |
| Onulet | Anson Maddocks | | U | Antiquities |
| 161 | Onulet | Anson Maddocks | | C | Masters Edition |
| 219 | Onulet | Anson Maddocks | | C | Masters Edition IV |
| 218 | Onward | Grzegorz Rutkowski | Red | U | Amonkhet |
| 250 | Onward | Grzegorz Rutkowski | Red | U | Amonkhet Remastered |
| 81 | Onyx Goblet | rk post | Black | C | Shards of Alara |
| 103 | Onyx Mage | Izzy | Black | U | Magic 2012 |
| Onyx Talisman | Sandra Everingham | | U | Ice Age |
| 8 | Oona, Queen of the Fae | Adam Rex | Blue/Black | M | From the Vault: Legends |
| 54 | Oona, Queen of the Fae | Mila Pesic | Blue/Black | M | Secret Lair Drop |
| 98 | Oona, Queen of the Fae | Adam Rex | Blue/Black | R | Zendikar Rising Commander |
| 142 | Oona, Queen of the Fae | Adam Rex | Blue/Black | R | Wilds of Eldraine Commander |
| 172 | Oona, Queen of the Fae | Adam Rex | Blue/Black | R | Shadowmoor |
| 193 | Oona, Queen of the Fae | Adam Rex | Blue/Black | R | Modern Masters |
| 51 | Oona's Blackguard | Kev Walker | Black | U | Zendikar Rising Commander |
| 72 | Oona's Blackguard | Kev Walker | Black | U | Morningtide |
| 261 | Oona's Blackguard | Kev Walker | Black | U | Jumpstart |
| 173 | Oona's Gatewarden | Mike Dringenberg | Blue/Black | C | Shadowmoor |
| 27 | Oona's Grace | Rebecca Guay | Blue | C | Eventide |
| 63 | Oona's Grace | Rebecca Guay | Blue | C | Eternal Masters |
| 91 | Oona's Grace | Rebecca Guay | Blue | C | Commander 2019 |
| 85 | Oona's Prowler | Wayne Reynolds | Black | R | Double Masters 2022 |
| 133 | Oona's Prowler | Wayne Reynolds | Black | R | Lorwyn |
| 443 | Oona's Prowler | Wayne Reynolds | Black | R | Double Masters 2022 |
| 128 | Ooze Flux | Zoltan Boros | Green | R | Gatecrash |
| 143 | Ooze Garden | Anthony S. Waters | Green | R | Shards of Alara |
| 22 | Opal Acrolith | Robh Ruppel | White | U | Urza's Saga |
| 23 | Opal Archangel | Jeff Miracola | White | R | Urza's Saga |
| 15 | Opal Avenger | Edward P. Beard, Jr. | White | R | Urza's Legacy |
| 24 | Opal Caryatid | Berry | White | C | Urza's Saga |
| 16 | Opal Champion | Edward P. Beard, Jr. | White | C | Urza's Legacy |
| 25 | Opal Gargoyle | Kev Walker | White | C | Urza's Saga |
| 30 | Opal Guardian | Christopher Rush | White | R | Time Spiral |
| 16 | Opal Lake Gatekeepers | Seb McKinnon | Blue | C | Dragon's Maze |
| 116 | Opal Palace | Andreas Rocha | | C | Kaldheim Commander |
| 172 | Opal Palace | Andreas Rocha | | C | Kamigawa: Neon Dynasty Commander |
| 259 | Opal Palace | Andreas Rocha | | C | Commander Anthology 2018 |
| 262 | Opal Palace | Andreas Rocha | | C | Commander Anthology |
| 266 | Opal Palace | Andreas Rocha | | C | Commander 2017 |
| 286 | Opal Palace | Logan Feliciano | | C | Warhammer 40,000 Commander |
| 306 | Opal Palace | Andreas Rocha | | C | Commander 2021 |
| 310 | Opal Palace | Andreas Rocha | | C | Commander 2013 Edition |
| 312 | Opal Palace | Andreas Rocha | | C | Commander 2016 |
| 352 | Opal Palace | Andreas Rocha | | C | Commander Legends |
| 361 | Opal Palace | Andreas Rocha | | C | Modern Horizons 3 Commander |
| 422 | Opal Palace | John Avon | | C | Commander Masters |
| 707 | Opal Palace | Andreas Rocha | | C | Commander Legends |
| 26 | Opal Titan | Paolo Parente | White | R | Urza's Saga |
| 13 | Opalescence | John Avon | White | R | Urza's Destiny |
| 17 | Opal-Eye, Konda's Yojimbo | Greg Staples | White | R | Betrayers of Kamigawa |
| 141 | Opaline Bracers | Anthony S. Waters | | C | Fifth Dawn |
| 244 | Opaline Sliver | Dave Dorman | White/Blue | U | Time Spiral |
| 213 | Opaline Unicorn | Christine Choi | | C | Conspiracy: Take the Crown |
| 218 | Opaline Unicorn | Christine Choi | | C | Theros |
| 105 | Open Fire | Jason Kang | Red | C | Hour of Devastation |
| 169 | Open Fire | Jason Kang | Red | C | Amonkhet Remastered |
| 34 | Open into Wonder | Tyler Jacobson | Blue | U | Zendikar Rising Commander |
| 64 | Open into Wonder | Tyler Jacobson | Blue | U | Amonkhet |
| 32 | Open the Armory | Steve Prescott | White | U | Shadows over Innistrad |
| 34 | Open the Armory | Steve Prescott | White | U | Commander Legends |
| 133 | Open the Gates | John Thacker | Green | C | Ravnica Allegiance |
| 151 | Open the Gates | John Thacker | Green | C | Ravnica Remastered |
| 112 | Open the Graves | Vincent Proce | Black | R | Core Set 2019 |
| 126 | Open the Graves | Vincent Proce | Black | R | Innistrad: Midnight Hunt Commander |
| 143 | Open the Omenpaths | Eric Deschamps | Red | C | Kaldheim |
| 21 | Open the Vaults | Brian Despain | White | R | Magic 2010 |
| 24 | Open the Vaults | Brian Despain | White | R | Double Masters |
| 72 | Open the Vaults | Brian Despain | White | R | Commander 2016 |
| 77 | Open the Vaults | Brian Despain | White | R | Commander 2015 |
| 168 | Open the Vaults | Ilker Yildiz | White | R | Magic The Gathering—Fallout |
| 455 | Open the Vaults | Ilker Yildiz | White | R | Magic The Gathering—Fallout |
| 23 | Open the Way | Livia Prima | Green | R | March of the Machine: The Aftermath |
| 73 | Open the Way | Daren Bader | Green | R | March of the Machine: The Aftermath |
| 123 | Open the Way | Livia Prima | Green | R | March of the Machine: The Aftermath |
| 163 | Open the Way | Livia Prima | Green | R | March of the Machine: The Aftermath |
| 118 | Opening Ceremony | Greg Bobrowski | Red | M | Unfinity (Acorn) |
| Ophidian | Cliff Nielsen | Blue | C | Weatherlight |
| 9 | Ophidian | Cliff Nielsen | Blue | C | Duel Decks Anthology, Jace vs. Chandra |
| 9 | Ophidian | Cliff Nielsen | Blue | C | Duel Decks: Jace vs. Chandra |
| 84 | Ophidian | Cliff Nielsen | Blue | C | Vintage Masters |
| 70 | Ophidian Eye | Zoltan Boros & Gabor Szikszai | Blue | C | Time Spiral |
| 84 | Ophiomancer | John Stanko | Black | R | Commander 2013 Edition |
| 276 | Ophiomancer | John Stanko | Black | R | Modern Horizons 3 |
| 452 | Ophiomancer | John Stanko | Black | R | Jumpstart 2022 |
| Opportunist | Dan Frazier | Red | U | Tempest |
| 133 | Opportunistic Dragon | Chris Rahn | Red | R | Throne of Eldraine |
| 134 | Opportunistic Dragon | Chris Rahn | Red | R | Adventures in the Forgotten Realms Commander |
| Opportunity | Ron Spears | Blue | U | Battle Royale Box Set |
| 37 | Opportunity | Ron Spears | Blue | U | Urza's Legacy |
| 45 | Opportunity | Allen Williams | Blue | U | Modern Masters 2017 Edition |
| 51 | Opportunity | Allen Williams | Blue | U | Commander 2013 Edition |
| 66 | Opportunity | Allen Williams | Blue | U | Magic 2014 Core Set |
| 89 | Opportunity | Allen Williams | Blue | U | Commander 2017 |
| 91 | Opportunity | Patrick Faricy | Blue | U | Seventh Edition |
| 126 | Opportunity | Allen Williams | Blue | U | Battlebond |
| 35 | Opposition | Svetlin Velinov | Blue | S | Masterpiece Series: Amonkhet Invocations |
| 40 | Opposition | Todd Lockwood | Blue | R | Urza's Destiny |
| 62 | Opposition | Todd Lockwood | Blue | R | Dominaria Remastered |
| 92 | Opposition | Mark Brill | Blue | R | Seventh Edition |
| 290 | Opposition | Todd Lockwood | Blue | R | Dominaria Remastered |
| 141 | Opposition Agent | Scott Murphy | Black | R | Commander Legends |
| 651 | Opposition Agent | Scott Murphy | Black | R | Commander Legends |
| 32 | Oppression | Matteo Bassini | Black | R | Wilds of Eldraine Enchanting Tales |
| 143 | Oppression | Pete Venters | Black | R | Urza's Saga |
| 152 | Oppression | Alex Horley-Orlandelli | Black | R | Seventh Edition |
| 19 | Oppressive Rays | Mark Zug | White | C | Journey into Nyx |
| 21 | Oppressive Rays | Mark Zug | White | C | Magic 2015 Core Set |
| 50 | Oppressive Will | Pat Lee | Blue | C | Saviors of Kamigawa |
| 19 | Opt | Kristina Collantes | Blue | U | Strixhaven Mystical Archive |
| 59 | Opt | Tyler Jacobson | Blue | C | Core Set 2021 |
| 59 | Opt | Dan Scott | Blue | C | Throne of Eldraine |
| 60 | Opt | Tyler Jacobson | Blue | C | Dominaria |
| 64 | Opt | John Howe | Blue | C | Invasion |
| 65 | Opt | Craig J Spearing | Blue | C | Ixalan |
| 101 | Opt | Dan Scott | Blue | C | Wilds of Eldraine Commander |
| 104 | Opt | Dan Murayama Scott | Blue | C | Outlaws of Thunder Junction Commander |
| 111 | Opt | Jehan Choo | Blue | R | Secret Lair Drop |
| 194 | Opt | Erion Makuo | Blue | C | The Lord of the Rings: Tales of Middle Earth Commander |
| 332 | Opt | Dan Scott | Blue | C | Jumpstart 2022 |
| 512 | Opt | Tyler Jacobson | Blue | C | Magic: The Gathering Foundations |
| 197 | Optical Optimizer | Jason Felix | | U | Unstable |
| 21 | Optimistic Scavenger | Brian Valeza | White | U | Duskmourn: House of Horror |
| 288 | Optimistic Scavenger | Brian Valeza | White | U | Duskmourn: House of Horror |
| 13 | Optimus Prime, Autobot Leader | Volta Creation | White/Blue/Red | M | The Brothers' War Transformers Cards |
| 27 | Optimus Prime, Autobot Leader | Volta Creation | White/Blue/Red | M | The Brothers' War Transformers Cards |
| 13 | Optimus Prime, Hero | Volta Creation | White/Blue/Red | M | The Brothers' War Transformers Cards |
| 27 | Optimus Prime, Hero | Volta Creation | White/Blue/Red | M | The Brothers' War Transformers Cards |
| 223 | Opulent Palace | Adam Paquette | | U | Dominaria United Commander |
| 238 | Opulent Palace | Adam Paquette | | U | Khans of Tarkir |
| 260 | Opulent Palace | Adam Paquette | | U | Commander Anthology 2018 |
| 264 | Opulent Palace | Adam Paquette | | U | Commander 2019 |
| 267 | Opulent Palace | Adam Paquette | | U | Commander 2017 |
| 278 | Opulent Palace | Jonas De Ro | | U | Magic The Gathering—Fallout |
| 295 | Opulent Palace | Adam Paquette | | U | Ikoria Commander |
| 307 | Opulent Palace | Adam Paquette | | U | Outlaws of Thunder Junction Commander |
| 313 | Opulent Palace | Adam Paquette | | U | Commander 2016 |
| 1017 | Opulent Palace | Adam Paquette | | U | Commander Masters |
| Oracle en-Vec | Dan Frazier | White | R | Tempest |
| 103 | Oracle of Bones | Greg Staples | Red | R | Born of the Gods |
| 63 | Oracle of Dust | Jason Rainville | Blue | C | Battle for Zendikar |
| 154 | Oracle of Mul Daya | Vance Kovacs | Green | R | Double Masters 2022 |
| 172 | Oracle of Mul Daya | Vance Kovacs | Green | R | Zendikar |
| 200 | Oracle of Mul Daya | Vance Kovacs | Green | R | Outlaws of Thunder Junction Commander |
| 370 | Oracle of Mul Daya | Darrell Riche | Green | R | Double Masters 2022 |
| 415 | Oracle of Mul Daya | Vance Kovacs | Green | R | Jumpstart |
| 464 | Oracle of Mul Daya | Vance Kovacs | Green | R | Double Masters 2022 |
| 233 | Oracle of Nectars | Brandon Kitkouski | White/Green | R | Shadowmoor |
| 259 | Oracle of the Alpha | Nino Vecia | Blue | U | Mystery Booster 2: Convention Edition |
| 71 | Oracle of Tragedy | Pavel Kolomeyets | Blue | U | March of the Machine |
| 16 | Oracle's Attendants | Orizio Daniele | White | R | Nemesis |
| 30 | Oracle's Attendants | Dany Orizio | White | R | Ninth Edition |
| 32 | Oracle's Attendants | Dany Orizio | White | R | Eighth Edition |
| 47 | Oracle's Insight | Raymond Swanland | Blue | U | Born of the Gods |
| 127 | Oracle's Insight | Raymond Swanland | Blue | U | Battlebond |
| 234 | Oracle's Vault | Jonas De Ro | | R | Amonkhet |
| 374 | Oracle's Vault | Jonas De Ro | | R | Streets of New Capenna Commander |
| 233 | Orah, Skyclave Hierophant | Heonhwa Choe | White/Black | R | Zendikar Rising |
| 369 | Orah, Skyclave Hierophant | Heonhwa Choe | White/Black | R | Zendikar Rising |
| 16 | Oran-Rief Hydra | Chris Rahn | Green | R | Duel Decks: Nissa vs. Ob Nixilis |
| 69 | Oran-Rief Hydra | Chris Rahn | Green | R | Archenemy: Nicol Bolas |
| 181 | Oran-Rief Hydra | Chris Rahn | Green | R | Battle for Zendikar |
| 17 | Oran-Rief Invoker | Anastasia Ovchinnikova | Green | C | Duel Decks: Nissa vs. Ob Nixilis |
| 182 | Oran-Rief Invoker | Anastasia Ovchinnikova | Green | C | Battle for Zendikar |
| 198 | Oran-Rief Ooze | Daarken | Green | R | Zendikar Rising |
| 361 | Oran-Rief Ooze | Daarken | Green | R | Zendikar Rising |
| 54 | Oran-Rief Recluse | Lars Grant-West | Green | C | Duel Decks: Jace vs. Vraska |
| 173 | Oran-Rief Recluse | Lars Grant-West | Green | C | Zendikar |
| 174 | Oran-Rief Survivalist | Kev Walker | Green | C | Zendikar |
| 28 | Oran-Rief, the Vastwood | Mike Bierek | | R | Duel Decks: Elves vs. Inventors |
| 173 | Oran-Rief, the Vastwood | Mike Bierek | | R | Kamigawa: Neon Dynasty Commander |
| 221 | Oran-Rief, the Vastwood | Mike Bierek | | R | Zendikar |
| 263 | Oran-Rief, the Vastwood | Mike Bierek | | R | Commander Anthology |
| 296 | Oran-Rief, the Vastwood | Mike Bierek | | R | Ikoria Commander |
| 297 | Oran-Rief, the Vastwood | Mike Bierek | | R | Commander 2015 |
| 305 | Oran-Rief, the Vastwood | Mike Bierek | | R | Commander 2014 |
| 307 | Oran-Rief, the Vastwood | Mike Bierek | | R | Commander 2021 |
| 320 | Oran-Rief, the Vastwood | Mike Bierek | | R | Bloomburrow Commander |
| 28 | Orator of Ojutai | Zack Stella | White | U | Dragons of Tarkir |
| 67 | Orator of Ojutai | Zack Stella | White | U | Commander 2017 |
| 35 | Oraxid | Dave Dorman | Blue | C | Nemesis |
| 140 | Orazca Frillback | Simon Dominic | Green | C | Rivals of Ixalan |
| 416 | Orazca Frillback | Simon Dominic | Green | C | Jumpstart |
| 68 | Orazca Puzzle-Door | Cristi Balanescu | Blue | C | The Lost Caverns of Ixalan |
| 108 | Orazca Raptor | Jakub Kasper | Red | C | Rivals of Ixalan |
| 181 | Orazca Relic | Kieran Yanner | | C | Rivals of Ixalan |
| 213 | Orazca Relic | Kieran Yanner | | C | Adventures in the Forgotten Realms Commander |
| 157 | Orb of Dragonkind | Brian Valeza | Red | R | Adventures in the Forgotten Realms |
| 381 | Orb of Dragonkind | Brian Valeza | Red | R | Adventures in the Forgotten Realms |
| 156 | Orb of Dreams | Dany Orizio | | R | Betrayers of Kamigawa |
| 609 | Orb of Origin (playtest) | Drew Moss | | R | Mystery Booster 2: Convention Edition |